A Useful Reagent for the Beckmann Rearrangement and the Synthesis of Nitriles from Carboxamides : N, N'-Carbonyldiimidazole and Reactive Halides
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概要
- 論文の詳細を見る
Ketoximes undergo the Beckmann rearrangement and primary carboxamides are dehydrated to nitriles on treatment with N, N'-carbonyldiimidazole and an excess of reactive halide. The reaction can be carried out in high yields under neutral reaction conditions by a simple procedure ; quaternization of the imidazole ring with reactive halides effectively promotes the reaction.
- 公益社団法人日本薬学会の論文
- 1984-07-25
著者
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原田 弘
Central Research Laboratories, Kissei Pharmaceutical Co., Ltd.,
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飯塚 欣二
Central Research Laboratories, Kissei Pharmaceutical Co., Ltd.,
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上條 哲聖
Central Research Laboratories, Kissei Pharmaceutical Co., Ltd.,
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上條 哲聖
キッセイ薬品工業株式会社中央研究所
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上条 哲聖
キッセイ薬品工業中央研究所
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飯塚 欣二
Central Research Laboratories Kissei Pharmaceutical Co. Ltd.
-
原田 弘
Central Research Laboratories Kissei Pharmaceutical Co. Ltd.
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