Facile Reduction of Methionine Sulfoxide with Sulfur Trioxide/Iodide Ion System

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概要

• 論文の詳細を見る

• A new system for the facile reduction of Met(O) in protected peptides (dimethylformamide-sulfur trioxide complex/iodide ion) was introduced. Met(O) in protected Met-enkephalins and protected leucosulfakinins were reduced to Met within 1h by this system, and the reducing ability of this new system seemed comparable to or greater than that of the formerly reported dimethylformamide-sulfur trioxide complex/ethanedithiol system. The methylsulfinylbenzyl protecting group of Tyr was also reduced to a methylthiobenzyl group by this system.

• 公益社団法人日本薬学会の論文
• 1990-05-25

著者

• 二木 史朗

  徳島大学薬学部

• 二木 史朗

  Faculty Of Pharmaceutical Sciences The University Of Tokushima

• 北川 幸己

  Faculty of Pharmaceutical Sciences, Kyoto University

• 秋田 正

  Faculty of Pharmaceutical Sciences, Tokushima University

• 秋田 正

  Faculty Of Pharmaceutical Sciences The University Of Tokushima

• 北川 幸己

  Faculty Of Pharmaceutical Sciences University Of Tokushima

• 矢上 健

  Faculty of Pharmaceutical Sciences, The University of Tokushima

• 大家 孝志

  Faculty of Pharmaceutical Sciences, The University of Tokushima

• 小川 豊子

  Faculty of Pharmaceutical Sciences, The University of Tokushima

• 二木 史朗

  Faculty Of Pharmaceutical Sciences Kyoto University

• 大家 孝志

  Faculty Of Pharmaceutical Sciences The University Of Tokushima

• 小川 豊子

  Faculty Of Pharmaceutical Sciences The University Of Tokushima

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