Chemical Transformation of Protoberberines. XVII. Biomimetic Introduction of an Oxy Functionality at the C-10 Position in the Benzo[c]phenanthridine Skeleton : Synthesis of 2,3,7,8,10-Pentaoxygenated Benzo[c]phenanthridine Alkaloids, Chelilutine and Sangu

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概要

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• An efficient and biomimetic introduction of an oxy functionality at the C-10 position in the benzo[c]phenanthridine skeleton was developed by regioselective oxygenation with salcomine-oxygen. This biomimetic procedure was successfully applied to a synthesis of 2,3,7,8,10-pentaoxygenated benzo[c]phenanthridine alkaloids, chelilutine (8) and sanguilutine (18), from the corresponding 2,3,7,8-tetraoxygenated benzo[c]phenanthridines.

• 社団法人日本薬学会の論文
• 1991-05-25

著者

• 花岡 美代次

  Faculty of Pharmaceutical Sciences, Kanazawa University

• 花岡 美代次

  金沢大学薬学部

• 花岡 美代次

  Faculty Of Pharmaceutical Sciences Osaka University

• 花岡 美代次

  Faculty Of Pharmaceutical Sciences Kanazawa University

• 向 智里

  金沢大学薬学部

• 向 智里

  Faculty of Pharmaceutical Sciences, Kanazawa University

• 趙 元剤

  Faculty of Pharmaceutical Sciences, Kanazawa University

• 吉田 修治

  Faculty of Pharmaceutical Sciences, Kanazawa University

• 向 智里

  Faculty Of Pharmaceutical Sciences Osaka University

• 吉田 修治

  Faculty Of Pharmaceutical Sciences Kanazawa University

• 趙 元剤

  Faculty Of Pharmaceutical Sciences Kanazawa University

• 花岡 美代次

  Institute Of Natural Medicine University Of Toyama

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