The Heterocyclic Ring Fission and Dehydroxylation of Catechins and Related Compounds by Eubacterium sp.Strain SDG-2, a Human Intestinal Bacterium

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概要

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• A human intestinal bacterium, Eubacterium(E.)sp.strain SDG-2, was tested for its ability to metabolize various(3R)- and (3S)-flavan-3-ols and their 3-O-gallates. This bacterium cleaved the C-ring of(3R)- and(3S)-flavan-3-ols to give 1, 3-diphenylpropan-2-ol derivatives, but not their 3-O-gallates. Furthermore, E.sp.strain SDG-2 had the ability of p-dehydroxylation in the B-ring of(3R)-flavan-3-ols, such as(-)-catechin, (-)-epicatechin, (-)-gallocatechin and(-)-epigallocatechin, but not of(3S)-flavan-3-ols, such as(+)-catechin and(+)-epicatechin.

• 社団法人日本薬学会の論文
• 2001-12-01

著者

• MESELHY Meselhy

  Institute of Natural Medicine, Faculty of Pharmaceutical Sciences and Pharmaceutical University

• Qin Guo-Wei

  Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences

• Wang Li-quan

  Institute Of Natural Medicine Toyama Medical And Pharmaceutical University:shanghai Institute Of Mat

• Wang Li-quan

  富山医科薬科大学和漢薬研究所

• Min Byung-sun

  Coll. Of Pharmacy Catholic Univ. Of Daegu

• Min B‐s

  College Of Pharmacy Catholic University Of Daegu

• Min Byung

  Institute Of Natural Medicine Toyama Medical And Pharmaceutical University

• 花岡 美代次

  金沢大学薬学部

• Nakamura Norio

  Institute Of Natural Medicine University Of Toyama

• Li Yong

  Department Of Chemistry Pukyong National University

• HATTORI Masao

  Institute of Natural Medicine, University of Toyama

• MIN Byung-Sun

  Institute of Natural Medicine, Toyama Medical and Pharmaceutical University

• Li Y

  Institute Of Natural Medicine Toyama Medical And Pharmaceutical University

• Hattori Masao

  Institute Of Natural Medicine University Of Toyama

• Qin Guo-wei

  Shanghai Institute Of Materia Medica Chinese Academy Of Science

• LI Yan

  Institute of Natural Medicine, Toyama Medical and Pharmaceutical University

• Min Byung

  College Of Pharmacy Catholic University Of Daegu

• Nakamura N

  Institute Of Natural Medicine Toyama Medical And Pharmaceutical University

• Meselhy M

  Toyama Medical And Pharmaceutical Univ. Toyama Jpn

• Meselhy Meselhy

  Faculty Of Pharmacy Cairo University

• Meselhy Meselhy

  (present Address)faculty Of Pharmacy Cairo University

• Li Yan

  Institute Of Applied Physics Crest Japan Science And Technology Corporation (jst) University Of Tsuk

• Li Yan

  Key Laboratory Of Materials Physics Institute Of Solid State Physics Chinese Academy Of Sciences

• Li Y

  Graduate School Of Engineering Tottori University

• Li Yan

  Institute Of Medicinal Plant Development Chinese Academy Of Medical Sciences And Peking Union Medica

• Meselhy Meselhy

  Institute Of Natural Medicine Faculty Of Pharmaceutical Sciences And Pharmaceutical University

• Hattori Masao

  Institute Of Natural Medicine Faculty Of Pharmaceutical Sciences

• Qin Guo-wei

  Shanghai Inst. Of Materia Medica Shanghai Institutes For Biological Sciences

• Hattori Masao

  Metabolic Engineering Institute Of Natural Medicine University Of Toyama

• Nakamura Norio

  Institute Of Natural Medicine Toyama And Pharmaceutical University

• Nakamura Norio

  Institute Of Natural Medicine

• 花岡 美代次

  Institute Of Natural Medicine University Of Toyama

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