Flavanone and Flavonol Glycosides from the Leaves of Thevetia peruviana and Their HIV-1 Reverse Transcriptase and HIV-1 Integrase Inhibitory Activities
スポンサーリンク
概要
- 論文の詳細を見る
Two new fiavanone glucosides, (2R)- and (2S)-5-O-β-_D-glucopyranosyl-7,4'-dihydroxy-3',5'-dimethoxyfla-vanone[pervianoside I(3), peruvianoside II(4)] and a new flavonol glycoside, quercetin 3-O-{β-_D-glucopyranosyl-(1→2)-[α-_L-rhamnopyranosyl-(1→6)]-β-_D-galactopyranoside} (peruvianoside III, 13) were isolated from the leaves of Thevetia peraviana SCHUM., together with nine known flavonol glycosides and two known iridoid glucosides. The structures of all compounds were determined on the basis of chemical and spectroscopic methods. Their inhibitory effects against HIV-1 reverse transcriptase and HIV-1 integrase were also investigated.
- 社団法人日本薬学会の論文
- 2002-05-01
著者
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NAKAMURA Norio
富山医科薬科大学和漢薬研究所
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花岡 美代次
金沢大学薬学部
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Hattori Masao
Institute Of Natural Medicine University Of Toyama
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TEWTRAKUL Supinya
Faculty of Pharmaceutical Sciences, Prince of Songkla University
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TEWTRAKUL Supinya
Institute of Natural Medicine, Toyama Medical and Pharmaceutical University
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FUJIWARA Tamio
Shionogi Institute for Medical Science
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TEWTRAKUL Supinya
a Institute of Natural Medicine, Toyama Medical and Pharmaceutical University
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NAKAMURA Norio
a Institute of Natural Medicine, Toyama Medical and Pharmaceutical University
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HATTORI Masao
a Institute of Natural Medicine, Toyama Medical and Pharmaceutical University
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FUJIWARA Tamio
b Shionogi Institute for Medical Science
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SUPAVITA Tanomjit
C Department of Pharmacognosy and Pharmaceutical Botany Faculty of Pharmaceutical Sciences, Prince o
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Fujiwara T
B Shionogi Institute For Medical Science
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Nakamura N
Institute Of Natural Medicine Toyama Medical And Pharmaceutical University
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Tewtrakul Supinya
Faculty Of Pharmaceutical Sciences Prince Of Songkla University
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Hattori Masao
Metabolic Engineering Institute Of Natural Medicine University Of Toyama
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Supavita T
C Department Of Pharmacognosy And Pharmaceutical Botany Faculty Of Pharmaceutical Sciences Prince Of
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花岡 美代次
Institute Of Natural Medicine University Of Toyama
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