Anti-herpes simplex virus activities of traditional Chinese medicines, used in Yunnan and Tibetan provinces of China
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概要
- 論文の詳細を見る
雲南省及びチベット自治区で採集した168種の中国少数民族薬物の水及びメタノールエキスの抗HSV-1活性をプラーク減少法を用いて検討した。24種のエキスに抗HSV-1活性が認められ, さらにHSV-1を経皮感染させたマウスを用い, これらのエキスを約1週間経口投与した。その結果, Terminalia chebula (T42), Tripterygium hypoglaucum (Y42M), Moghania philippinensis (Y86M)のメタノールエキス, 及び, Tripterygium hypoglaucum (Y44H)の水エキスに有意な皮膚病変進展の遅延効果が認められた。また, Cassia fistula (T59), Choerospondias axillaries (T73)のメタノールエキス, 及び, Begonia evansiana (Y27H), Maytenus fookerii (Y60H), Potentilla griffithii (Y63H)の水エキスに生存期間の延長が認められた。これらのエキスには, 抗HSV-1活性を示す化合物が含まれており, 新規抗HSV-1化合物の探索に有用であると思われる。
- 和漢医薬学会の論文
- 2005-12-20
著者
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服部 征雄
富山大学和漢医薬学総合研究所
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NAKAMURA Norio
富山医科薬科大学和漢薬研究所
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Nakamura Norio
Institute Of Natural Medicine University Of Toyama
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Komatsu Katsuko
Institute of Natural Medicine, University of Toyama
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Hattori Masao
Department Of Metabolic Engineering Institute Of Natural Medicine Toyama Medical And Pharmaceutical
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JO Michiko
Institute of Natural Medicine, University of Toyama
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服部 征雄
富山大学・和漢医薬学総合研究所薬物代謝工学
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Kurokawa Masahiko
Department Of Biochemistry School Of Pharmaceutical Sciences Kyushu University Of Health And Welfare
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Kurokawa Masahiko
Department Of Virology University Of Toyama:(present Address) Department Of Biochemistry School Of P
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SHIRAKI Kimiyasu
Departments of Virology, Toyama Medical and Pharmaceutical University
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Komatsu Katsuko
Institute Of Natural Medicine University Of Toyama
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Komatsu Katsuko
Institute Of Natural Medical Toyama Medicine And Pharmaceutical University
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Shiraki Kimiyasu
Department Of Virology Graduate School Of Medicine And Pharmaceutical Sciences University Of Toyama
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Nakamura N
Toyama Medical And Pharmaceutical Univ. Toyama Jpn
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Komatsu Katsuko
Research Center Of Ethnomedicines Institute Of Natural Medicine Toyama Medical And Pharmaceutical Un
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Jo Michiko
Institute Of Natural Medicine University Of Toyama
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Shiraki K
Department Of Virology Graduate School Of Medicine And Pharmaceutical Sciences University Of Toyama
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Komatsu Katsuko
Inst. Of Natural Medicine Univ. Of Toyama
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Nakamura Norio
Institute Of Natural Medicine Toyama And Pharmaceutical University
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Nakamura Norio
Institute Of Natural Medicine Facully Of Pharmaceutical Sciences And Pharmaceutical University
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Nakamura Norio
Institute Of Natural Medicine
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Nakamura Norio
Institute of Natural Medicine, University of Toyama
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