Hydrolyzed Metabolites of Thalidomide : Synthesis and TNF-α Production-Inhibitory Activity

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概要

• 論文の詳細を見る

• Putative hydrolyzed metabolites of thalidomide were prepared and characterized, and their inhibitory activity on tumor necrosis factor (TNF)-α production in the human monocytic leukemia cell line THP-1 was evaluated. α-(2-Carboxybenzamido) glutarimide was a more potent TNF-α production inhibitor than thalidomide.

• 公益社団法人日本薬学会の論文
• 2007-04-01

著者

• Nakamura Takanori

  Institute Of Molecular & Cellular Biosciences The University Of Tokyo

• MIYACHI Hiroyuki

  Institute of Molecular & Cellular Biosciences, The University of Tokyo

• HASHIMOTO Yuichi

  Institute of Molecular & Cellular Biosciences, The University of Tokyo

• Hashimoto Yuichi

  Univ. Tokyo Tokyo Jpn

• Hashimoto Y

  Univ. Tokyo Tokyo Jpn

• Hashimoto Y

  Graduate School Of Pharmaceutical Sciences Kyushu University

• 中山 太ニ

  岡山大学薬学部薬剤学教室

• NOGUCHI Tomomi

  Institute of Molecular & Cellular Biosciences, The University of Tokyo

• Miyachi Hiroyuki

  Institute Of Molecular & Cellular Biosciences University Of Tokyo

• Hashimoto Yuichi

  Institute Of Molecular & Cellular Biosciences University Of Tokyo

• Hashimoto Yuichi

  Institute Of Molecular And Cellular Biosciences The Universityv Of Tokyo

• Noguchi T

  Medicinal Research Laboratories Taisho Pharmaceutical Co. Ltd.

• Miyachi H

  Institute Of Molecular & Cellular Biosciences The University Of Tokyo

• Miyachi Hiroyuki

  Div. Of Pharmaceutical Sciences Graduate School Of Medicine Dentistry And Pharmaceutical Sciences Ok

• Noguchi-yachide Tomomi

  Institute Of Molecular & Cellular Biosciences The University Of Tokyo

• Hashimoto Y

  Institute Of Molecular & Cellular Biosciences The University Of Tokyo

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