Identification of Binding Proteins of Fusarielin A as Actin and Tubulin
スポンサーリンク
概要
- 論文の詳細を見る
Fusarielin A (FSA), isolated from culture of Fusarium sp. K432, has anti-fungal/anti-angiogenic activity. Based on our previous structure–activity relationship studies, we prepared FSA-immobilized affinity gel. The results of affinity chromatography with this gel indicated that tubulin and actin are FSA-binding proteins. The binding affinities of tubulin and actin for FSA were estimated by the use of surface plasmon resonance spectroscopy.
著者
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Aoyama Hiroshi
Institute Of Molecular & Cellular Biosciences The University Of Tokyo
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KOBAYASHI Hisayoshi
Institute of Molecular & Cellular Biosciences, The University of Tokyo
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HASHIMOTO Yuichi
Institute of Molecular & Cellular Biosciences, The University of Tokyo
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Dodo Kosuke
RIKEN
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HORI Masatoshi
Graduate School of Agriculture and Life Sciences, The University of Tokyo
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FUJIMOTO Haruka
Institute of Molecular & Cellular Biosciences, The University of Tokyo
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NOGUCHI-YACHIDE Tomomi
Institute of Molecular & Cellular Biosciences, The University of Tokyo
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KOBAYASHI Hisayoshi
Institute of Molecular and Cellular Biosciences, The University of Tokyo
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Fujimoto Haruka
Institute of Molecular and Cellular Biosciences, The University of Tokyo
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Aoyama Hiroshi
Institute of Molecular and Cellular Biosciences, The University of Tokyo
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Hori Masatoshi
Graduate School of Agricultural and Life Sciences, The University of Tokyo
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