Antiangiogenic Activity of Tumor Necrosis Factor-α Production Regulators Derived from Thalidomide

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概要

• 論文の詳細を見る

• Recently, we developed novel tumor necrosis factor (TNF)-α production regulators with a phthalimide skeleton derived fromthalidomide. We show here that some of these compounds are more potent inhibitors than thalidomide of angiogenesis induced by basic fibroblast growth factor in a murine angiogenesis assay.

• 公益社団法人日本薬学会の論文
• 1999-02-15

著者

• MIYACHI Hiroyuki

  Institute of Molecular & Cellular Biosciences, The University of Tokyo

• HASHIMOTO Yuichi

  Institute of Molecular & Cellular Biosciences, The University of Tokyo

• Hashimoto Yuichi

  Univ. Tokyo Tokyo Jpn

• Hashimoto Y

  Graduate School Of Pharmaceutical Sciences Kyushu University

• SHIMAZAWA Rumiko

  Institute of Molecular & Cellular Biosciences, The University of Tokyo

• TAKAYAMA Hisae

  Institute of Molecular and Cellular Biosciences University of Tokyo

• KATO Fuminori

  R&D Group for Pharmaceuticals, Central Research Institute, Ishihara Sangyo Kaisha Ltd.,

• KATO Masanari

  R&D Group for Pharmaceuticals, Central Research Institute, Ishihara Sangyo Kaisha Ltd.,

• Miyachi Hiroyuki

  Institute Of Molecular & Cellular Biosciences University Of Tokyo

• Hashimoto Yuichi

  Institute Of Molecular & Cellular Biosciences University Of Tokyo

• Takayama Hiromitsu

  Laboratory Of Molecular Structure And Biological Function Graduate School Of Pharmaceutical Sciences

• Kuroda Kensei

  R&d Group For Pharmaceuticals Central Research Institute Ishihara Sangyo Kaisha Ltd.

• Kato F

  R&d Group For Pharmaceuticals Central Research Institute Ishihara Sangyo Kaisha Ltd.

• Kato Masanari

  R&d Group For Pharmaceuticals Central Research Institute Ishihara Sangyo Kaisha Ltd.

• KURODA Kensei

  R&D Group for Pharmaceuticals, Central Research Institute, Ishihara Sangyo Kaisha Ltd.,

• Shimazawa R

  Institute Of Molecular & Cellular Biosciences The University Of Tokyo

• Miyachi H

  Institute Of Molecular & Cellular Biosciences The University Of Tokyo

• Miyachi Hiroyuki

  Div. Of Pharmaceutical Sciences Graduate School Of Medicine Dentistry And Pharmaceutical Sciences Ok

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