Inhibition of Restriction Enzymes EcoRI, BamHI and HindIII by Phenethylphenylphthalimides Derived from Thalidomide
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概要
- 論文の詳細を見る
We discovered inhibitors of the restriction enzymes EcoRI, BamHI and HindIII by screening our library of compounds with a phenethylphenylphthalimide skeleton, based on α-glucosidase inhibitors and liver X receptor antagonists derived from thalidomide. Structural development afforded the potent restriction enzyme inhibitors 25 and 26.
- 公益社団法人 日本薬学会の論文
著者
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HASHIMOTO Yuichi
Institute of Molecular & Cellular Biosciences, The University of Tokyo
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Motoshima Kazunori
Institute of Molecular & Cellular Biosciences, The University of Tokyo
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Ishikawa Minoru
Institute of Molecular & Cellular Biosciences, The University of Tokyo
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Sugita Kazuyuki
Institute of Molecular & Cellular Biosciences, The University of Tokyo
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Harada Yuichi
Center For Influenza Virus Research National Institute Of Infectious Diseases
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Ishikawa Minoru
Institute Of Molecular & Cellular Biosciences The University Of Tokyo
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Sugita Kazuyuki
Institute of Molecular & Cellular Biosciences, The University of Tokyo
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