Synthesis of a Tetradecapeptide corresponding to Sequence 90-103 of Bovine Adrenodoxin

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概要

• 論文の詳細を見る

• Two tetradecapeptides, Z-Leu-Gly-Cys (Bzl)-Gln-Ile-Cys (Bzl)-Leu-Thr-Lys (Z)-Ala-Met-Asp (OBzl)-Asn-Met-OH (I) and its benzyl ester (VIII) were synthesized. I was synthesized by the condensation of two heptapeptides [Z-Leu-Gly-Cys (Bzl)-Gln-Ile-Cys (Bzl)-Leu-NHNH_2 (II) and Boc-Thr-Lys (Z)-Ala-Met-Asp (OBzl)-Asn-Met-OH (III)], while VIII was synthesized stepwise by the condensation of 4 fragments [Z-Leu-Gly-Cys (Bzl)-Gln-OH (XI), Boc-Ile-Cys (Bzl)-Leu-OH (X), Boc-Thr-Lys (Z)-Ala-NHNH_2 (IV) and Boc-Met-Asp (OBzl)-Asn-Met-OBzl (IX)]. Deblocked I and deblocked VIII each formed a chelate with iron and sulfur.

• 社団法人日本薬学会の論文
• 1980-07-25

著者

• 岡田 芳男

  Faculty of Pharmaceutical Sciences Kobe-Gakuin University

• 川崎 紘一

  Faculty of Pharmaceutical Sciences, Kobe Gakuin University

• 前田 光子

  Faculty of Pharmaceutical Sciences, Kobe Gakuin University

• 川崎 知恵

  Faculty of Pharmaceutical Sciences, Kobe-Gakuin University

• 川崎 知恵

  Faculty Of Pharmaceutical Sciences Kobe-gakuin University

• Maeda M

  Department Of Pharmacology Faculty Of Pharmaceutical Sciences Nagasaki University:faculty Of Pharmac

• Kawasaki Keiko

  Biological Science Laboratories Kao Corporation

• 川崎 紘一

  Faculty Of Pharmaceutical Sciences & Cooperative Research Center Of Life Sciences Kobe Gakuin Un

• Maeda Masatomo

  Laboratory Of Biochemistry And Molecular Biology Graduate School Of Pharmaceutical Sciences Osaka Un

関連論文

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