Amino Acids and Peptides. XIII. Synthetic Studies on N-Terminal Tripeptide Amide Analogs of Fibrin α-Chain

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概要

• 論文の詳細を見る

• N-Terminal tripeptide analogs of fibrin α-chain were synthesized and their inhibitory effect on fibrinogen/thrombin clotting was examined. A new water-soluble active ester, 3-pyridinium ester, was used for the synthesis. Among the synthetic peptides, H-Gly-Pro-Arg-hexamethyleneimine exhibited the highest inhibitory effect on fibrinogen-thrombin clotting.

• 公益社団法人日本薬学会の論文
• 1991-03-25

著者

• 川崎 紘一

  Faculty of Pharmaceutical Sciences, Kobe Gakuin University

• 辻 俊樹

  Faculty of Pharmaceutical Sciences, Kobe-Gakuin University

• 平瀬 克彦

  Faculty of Pharmaceutical Sciences, Kobe-Gakuin University

• 宮野 雅範

  Faculty of Pharmaceutical Sciences, Kobe-Gakuin University

• 岩本 雅博

  Research Institute Daiichi Seiyaku Co. Ltd.

• 岩本 政博

  Research Institute Daiichi Seiyaku Co.. Ltd.

• 辻 俊樹

  Faculty Of Pharmaceutical Sciences Kobe-gakuin University

• 宮野 雅範

  Faculty Of Pharmaceutical Sciences Kobe-gakuin University

• 平瀬 克彦

  Faculty Of Pharmaceutical Sciences Kobe-gakuin University

• 井本 芳則

  Faculty of Pharmaceutical Sciences, Kobe-Gakuin University

• Kawasaki Keiko

  Biological Science Laboratories Kao Corporation

• 井本 芳則

  Faculty Of Pharmaceutical Sciences Kobe-gakuin University

• 川崎 紘一

  Faculty Of Pharmaceutical Sciences & Cooperative Research Center Of Life Sciences Kobe Gakuin Un

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