Effects of Tea Catechins on Diet-induced Obesity in Mice〔和文〕
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概要
- 論文の詳細を見る
Examination was made of the effects of tea catechins (TC) on diet-induced obesity. Exposure to high-fat-diet (30% fat) in C57BL/6J mice for 4 weeks induced significant increase in body weight, visceral fat (epididymal, mesenteric, retroperitoneal, perinephric) weight and plasma concentrations of glucose, triacylglycerol and leptin, compared to low-fat diet (5% fat). Treatment with 0.1%TC (high-fat diet +0.1%TC group) had little effect on diet-induced obesity. Relative to high-fat diet and 0.1%TC treatment, 0.5%TC treatment (high-fat diet +0.5%TC group) was noted to bring about significant decrease in body weight, visceral, fat weights and plasma leptin. Lipid absorption rate was the same with the high fat diet and 0.5%TC treatment. An oral soluble starch and sucrose (SS-S) tolerance test was conducted on C57BL/6J mice to evaluate the effects of TC to sugar absorption. When the ratio of TC to sum of SS-S was the same as that in the diet composition for the 0.5%TC treatment, the plasma glucose level showed no response. These results demonstrate for the first time TC to have antiobesity effects on diet-induced obesity in mice, and suggest these effects to be exerted through a mechanism that would not involve inhibition of intestinal absorption of sugar and lipid.
- 日本油化学会の論文
- 2001-07-01
著者
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Shimasaki Hiroyuki
Department of Health and Nutrition, University of Human Arts and Sciences
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Itakura H
Department Of Food Science Ibaraki Christian University
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Itakura Hiroshige
コカコーラ東京研究開発センター
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Itakura Hiroshige
明治製菓
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Itakura H
Ibaraki Christian Univ. Ibaraki Jpn
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ITAKURA Hiroshige
National Institute of Health and Nutrition
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TOKIMITSU Ichiro
Biological Science Laboratories, Kao Corp.
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Itakura H
National Inst. Health And Nutrition Tokyo Jpn
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Hase Tadashi
Health Care Products Research Laboratories No.1 Kao Corporation
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Shimasaki H
Teikyo Univ. School Of Medicine Tokyo Jpn
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川崎 紘一
Life Science Center Faculty Of Pharmaceutical Sciences Kobe Gakuin University
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Itakura Hiroshige
Department Of Food Sciences Ibaraki Christian University
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Itakura Hiroshige
Division Of Clinical Nutrition National Institute Of Health And Nutrition
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MEGURO Shinichi
Biological Science Laboratories, Kao Corporation
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KOMINE Yumiko
Biological Science Laboratories, Kao Corporation
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HASE Tadashi
Biological Science Laboratories, Kao Corporation
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YUZAWA Masayuki
Biological Science Laboratories, Kao Corporation
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MIZUNO Tomohito
Biological Science Laboratories, Kao Corporation
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ONIZAWA Kouji
Biological Science Laboratories, Kao Corporation
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KAWASAKI Keiko
Biological Science Laboratories, Kao Corporation
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NAKAGIRI Hideaki
Biological Science Laboratories, Kao Corporation
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MATSUI Yuji
Biological Science Laboratories, Kao Corporation
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SUZUKI Junko
Biological Science Laboratories, Kao Corporation
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Itakura H
Division Of Clinical Nutrition National Institute Of Nutrition And Health
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Itakura Hiroshige
Department Of Food Science Ibaraki Christian University
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Shimasaki Hiroyuki
Department Of Biochemistry Teikyo University School Of Medicine
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Kawasaki Koichi
Department Of Pharmacology Faculty Of Pharmaceutical Sciences Nagasaki University:faculty Of Pharmac
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Tokimitsu Ichiro
Health Care Food Research Laboratories Kao Corporation
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Tokimitsu Ichiro
Biological Science Laboratories Kao Corporation
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Yuzawa Masayuki
Biological Science Laboratories Kao Corporation
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Hase Tadashi
Biological Science Laboratories Kao Corporation
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Takase Hideto
Health Care Products Research Laboratories No.1 Kao Corporation
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Onizawa Kouji
Biological Science Laboratories Kao Corporation
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Komine Yumiko
Biological Science Laboratories Kao Corporation
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Komine Yumiko
Japan Aviation Electronics Industry Ltd.
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Shimasaki Hiroyuki
帝京大医第一生化
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Kawasaki Keiko
Biological Science Laboratories Kao Corporation
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Meguro Shinichi
Biological Science Laboratories Kao Corporation
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Shimasaki H
Dep. Of Health And Nutrition Univ. Of Arts And Sciences
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Nakagiri Hideaki
Biological Sci. Laboratories Kao Corp.
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Suzuki Junko
Biological Science Laboratories Kao Corporation
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