Amino Acids and Peptides. XXI. Laminin-Related Peptide Analogs Including Poly(Ethylene Glycol) Hybrids and Their Inhibitory Effect on Experimental Metastasis
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概要
- 論文の詳細を見る
Laminin-related peptides, Try-Ile-Gly-Ser-Arg analogs, were prepared and their inhibitory effects on experimental metastasis were examined. Of the amino acids in the Tyr-Ile-Gly-Ser-Arg sequence, L-Arg was very important and Ile was not essential for the inhibitory effect. To obtain a potent inhibitor of metastasis, hybrids of Tyr-Ile-Gly-Ser-Arg-Gly and 2 types of poly(ethylene glycol) were prepared. The inhibitory effects of the hybrids were more potent than that of Tyr-Ile-Gly-Ser-Arg-Gly.
- 社団法人日本薬学会の論文
- 1994-04-15
著者
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真弓 忠範
Faculty of Pharmaceutical Sciences
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濱 堯夫
Faculty of Pharmaceutical Sciences
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川崎 紘一
Faculty of Pharmaceutical Sciences, Kobe Gakuin University
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並川 眞知子
Faculty of Pharmaceutical Sciences, Kobe Gakuin University
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水田 豊彦
Faculty of Pharmaceutical Sciences, Kobe Gakuin University
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山本 晋
Faculty of Pharmaceutical Sciences, Osaka University
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並川 真知子
Faculty of Pharmaceutical Sciences, Kobe Gakuin University
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山城 祐子
Faculty of Pharmaceutical Sciences, Kobe Gakuin University
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岩井 雄二
Faculty of Pharmaceutical Sciences, Kobe Gakuin University
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村上 智彦
Faculty of Pharmaceutical Sciences, Kobe Gakuin University
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山城 祐子
Faculty Of Pharmaceutical Sciences Kobe Gakuin University
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村上 智洋
Faculty Of Pharmaceutical Sciences Kobe Gakuin University
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村上 智彦
神戸学院大学 薬
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山本 譲
Faculty Of Pharmaceutical Sciences Kanazawa University
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YAMAMOTO Shinobu
Showa College of Pharmaceutical Sciences
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川崎 紘一
Life Science Center Faculty Of Pharmaceutical Sciences Kobe Gakuin University
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Yamamoto Shuhei
Department Of Chemistry Graduate School Of Science Osaka City University
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山本 晋
Faculty Of Pharmaceutical Sciences Osaka University
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Yamamoto Y
Tohoku Univ. Sendai Jpn
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Yamamoto Y
Pharmaceutical Research Laboratory Hokuriku Seiyaku Co. Ltd.
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Yamamoto Y
School Of Pharmaceutical Sciences Toho University
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岩井 雄二
Faculty Of Pharmaceutical Sciences Kobe Gakuin University
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水田 豊彦
Faculty Of Pharmaceutical Sciences Kobe Gakuin University
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Yamamoto Yoshio
Pharmaceutical Research Division Takeda Chemical Industries Ltd.
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並川 真知子
Faculty Of Pharmaceutical Sciences Kobe Gakuin University
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Yamamoto Y
大阪薬科大学
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Iwai Y
Kitasato Institute For Life Sciences Kitasato University
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Yamamoto Shozo
Department Of Biochemistry Tokushima University School Of Medicine
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Kawasaki Keiko
Biological Science Laboratories Kao Corporation
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Hama T
Pharmaceutical Development And Research Laboratories Teikoku Seiyaku Co. Ltd.
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浜 堯夫
Faculty Of Pharmaceutical Sciences Kobe Gakuin University
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川崎 紘一
Faculty Of Pharmaceutical Sciences & Cooperative Research Center Of Life Sciences Kobe Gakuin Un
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山本 靖夫
School Of Pharmaceutical Sciences Toho University
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