Quantitative Determination of Ergothioneine in Plasma and Tissues by TLC-Densitometry
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概要
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A rapid and reliable thin-layer chromatographic (TLC) method for the quantitative analysis of ergothioneine in plasma and in various organs is presented. After extraction from biological materials with acetone/methanol (1 : 1), ergothioneine was separated by TLC and the spot corresponding to the compound with Rf 0.29 was quantified by scanning with a densitometer at 256 nm. The sensitivity of the assay was 0.05 μg/20μl of liver extract. This procedure should be useful in pharmacokinetic studies of ergothioneine in relation to its physiological role.
- 社団法人日本薬学会の論文
- 1980-10-25
著者
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真弓 忠範
Faculty of Pharmaceutical Sciences
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真弓 忠範
Faculty Of Pharmaceutical Sciences Osaka University
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金子 郁枝
Faculty of Pharmaceutical Sciences, Kobe Gakuin University
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竹内 由和
Faculty of Pharmaceutical Sciences, Kobe Gakuin University
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山岡 由美子
Faculty of Pharmaceutical Sciences, Kobe Gakuin University
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田中 裕美子
Faculty of Pharmaceutical Sciences, Kobe Gakuin University
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福田 友昭
Faculty of Pharmaceutical Sciences, Kobe Gakuin University
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福森 義信
Faculty of Pharmaceutical Sciences, Kobe Gakuin University
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浜 堯夫
Faculty of Pharmaceutical Sciences, Kobe Gakuin University
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金子 郁枝
Faculty Of Pharmaceutical Sciences Kobe Gakuin University
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竹内 由和
神戸学院大学薬学部臨床薬学部門薬剤学研究室
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山岡 由美子
Department Of Parmaceutics Faculty Of Pharmaceutical Sciences Kobe-gakuin University
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田中 裕美子
Faculty Of Pharmaceutical Sciences Kobe Gakuin University
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竹内 由和
Department Of Parmaceutics Faculty Of Pharmaceutical Sciences Kobe-gakuin University
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Takeuchi Yoshikazu
Department Of Pharmaceutics Faculty Of Pharmaceutical Sciences Kobe Gakuin University
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福森 義信
神戸学院大学 薬学部
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福田 友昭
Faculty Of Pharmaceutical Sciences Kobe Gakuin University
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竹内 由和
Faculty Of Pharmaceutical Sciences Kobe-gakuin University
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浜 尭夫
神戸学院大学 薬
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山岡 由美子
Faculty Of Pharmaceutical Sciences Kobe-gakuin University
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浜 堯夫
Faculty Of Pharmaceutical Sciences Kobe Gakuin University
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