Studies on Ergothioneine. X. Effects of Ergothioneine on the Hepatic Drug Metabolizing Enzyme System and on Experimental Hepatic Injury in Rats
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概要
- 論文の詳細を見る
When ergothioneine was administered to rats for 7 d, the pentobarbital sleeping time was reduced significantly. This action was specific to ergothioneine and was not shown by various ergothioneine-related compounds (cysteine, glutathione, carnitine and histidine). This action of ergothioneine did not appear to be caused by induction of the drug-metabolizing enzyme system. The level of ergothioneine in the liver decreased markedly when phenobarbital or ethionine was administered to rats. Ergothioneine inhibited hepatic injury and significantly decreased the level of lipid peroxide induced by ethionine administration.
- 社団法人日本薬学会の論文
- 1983-05-25
著者
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真弓 忠範
Faculty of Pharmaceutical Sciences
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河合 裕一
Faculty of Pharmaceutical Sciences
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川野 博子
Faculty of Pharmaceutical Sciences
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濱 堯夫
Faculty of Pharmaceutical Sciences
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真弓 忠範
Faculty Of Pharmaceutical Sciences Osaka University
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趙 啓
Faculty of Pharmaceutical Sciences, Kobe-Gakuin University
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春名 康代
Faculty of Pharmaceutical Sciences, Kobe-Gakuin University
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川野 博子
Faculty Of Pharmaceutical Sciences Kobe-gakuin University
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河合 裕一
Faculty Of Pharmaceutical Sciences Kobe-gakuin University
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浜 尭夫
神戸学院大学 薬
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濱 尭夫
Faculty Of Pharmaceutical Sciences Kobe-gakuin University
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浜 堯夫
Faculty Of Pharmaceutical Sciences Kobe Gakuin University
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春名 康代
Faculty Of Pharmaceutical Sciences Kobe-gakuin University
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趙 啓
Faculty Of Pharmaceutical Sciences Kobe-gakuin University
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