Amino Acids and Peptides. XXV. Preparation of Fibronectin-Related Peptide Poly(ethylene glycol) Hybrids and Their Inhibitory Effect on Experimental Metastasis

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概要

• 論文の詳細を見る

• Hybrids of fibronectin-related peptides [Arg-Gly-Asp (RGD), Arg-Gly-Asp-Ser (RGDS)] and poly(ethylene glycol) (PEG) were prepared and their inhibitory effects on experimental metastasis in mice were examined. The inhibitory effect of RGD was markedly potentiated by hybrid formation with poly(ethylene glycol) #6000. As to inhibitory effect, RGD was more potent than RGDS and RGD PEG hybrids were superior to RGDS PEG hybrids. Hybrid formation with PEG #6000 was more effective than that with PEG #4000.

• 社団法人日本薬学会の論文
• 1995-12-15

著者

• 提 康央

  Faculty Of Pharmaceutical Sciences Osaka University

• 真弓 忠範

  Faculty of Pharmaceutical Sciences

• 濱 堯夫

  Faculty of Pharmaceutical Sciences

• 川崎 紘一

  Faculty of Pharmaceutical Sciences, Kobe Gakuin University

• 山本 晋

  Faculty of Pharmaceutical Sciences, Osaka University

• 中川 晋作

  Faculty of Pharmaceutical Sciences, Osaka University

• 並川 真知子

  Faculty of Pharmaceutical Sciences, Kobe Gakuin University

• 山城 祐子

  Faculty of Pharmaceutical Sciences, Kobe Gakuin University

• 岩井 雄二

  Faculty of Pharmaceutical Sciences, Kobe Gakuin University

• 山城 祐子

  Faculty Of Pharmaceutical Sciences Kobe Gakuin University

• 山本 譲

  Faculty Of Pharmaceutical Sciences Kanazawa University

• YAMAMOTO Shinobu

  Showa College of Pharmaceutical Sciences

• 川崎 紘一

  Life Science Center Faculty Of Pharmaceutical Sciences Kobe Gakuin University

• 中川 晋作

  Faculty Of Pharmaceutical Sciences Kobe Gakuin University

• Yamamoto Shuhei

  Department Of Chemistry Graduate School Of Science Osaka City University

• 山本 晋

  Faculty Of Pharmaceutical Sciences Osaka University

• Yamamoto Y

  School Of Pharmaceutical Sciences Toho University

• 浜 尭夫

  神戸学院大学 薬

• 濱 堯夫

  Faculty Of Pharmaceutical Sciences Kobe Gakuin University

• 岩井 雄二

  Faculty Of Pharmaceutical Sciences Kobe Gakuin University

• Yamamoto Yoshio

  Pharmaceutical Research Division Takeda Chemical Industries Ltd.

• 並川 真知子

  Faculty Of Pharmaceutical Sciences Kobe Gakuin University

• 堤 康央

  医薬基盤研究所:大阪大学大学院薬学研究科:大阪大学臨床医工学融合研究教育センター

• Yamamoto Y

  大阪薬科大学

• Iwai Y

  Kitasato Institute For Life Sciences Kitasato University

• Yamamoto Shozo

  Department Of Biochemistry Tokushima University School Of Medicine

• Kawasaki Keiko

  Biological Science Laboratories Kao Corporation

• 浜 堯夫

  Faculty Of Pharmaceutical Sciences Kobe Gakuin University

• 川崎 紘一

  Faculty Of Pharmaceutical Sciences & Cooperative Research Center Of Life Sciences Kobe Gakuin Un

• 山本 靖夫

  School Of Pharmaceutical Sciences Toho University

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