Amino Acids and Peptides. XVIII. Synthetic Peptides Related to N-Terminal Portion of Fibrin α-Chain and Their Inhibitory Effect on Fibrinogen/Thrombin Clotting
スポンサーリンク
概要
- 論文の詳細を見る
Peptide analogs of the N-terminal portion of fibrin α-chain were prepared and their inhibitory effects on fibrinogen/thrombin clotting were examined. Of the synthetic peptides, H-Gly-Pro-Arg-Pro-Pro-NH_2 exhibited the most potent inhibitory effect.
- 公益社団法人日本薬学会の論文
- 1993-05-15
著者
-
川崎 紘一
Faculty of Pharmaceutical Sciences, Kobe Gakuin University
-
平瀬 克彦
Faculty of Pharmaceutical Sciences, Kobe-Gakuin University
-
宮野 雅範
Faculty of Pharmaceutical Sciences, Kobe-Gakuin University
-
岩本 雅博
Research Institute Daiichi Seiyaku Co. Ltd.
-
岩本 政博
Research Institute Daiichi Seiyaku Co.. Ltd.
-
宮野 雅範
Faculty Of Pharmaceutical Sciences Kobe-gakuin University
-
平瀬 克彦
Faculty Of Pharmaceutical Sciences Kobe-gakuin University
-
Kawasaki Keiko
Biological Science Laboratories Kao Corporation
-
川崎 紘一
Faculty Of Pharmaceutical Sciences & Cooperative Research Center Of Life Sciences Kobe Gakuin Un
関連論文
- Amino Acids and Peptides. XXVI. Laminin-Related Peptide Poly (Ethylene Glycol) Hybrids and Their Inhibitory Effect on Experimental Metastasis
- Amino Acids and Peptides. XXV. Preparation of Fibronectin-Related Peptide Poly(ethylene glycol) Hybrids and Their Inhibitory Effect on Experimental Metastasis
- Cell-Penetrating Peptides as Adenovirus Vector Carrier
- Amino Acids and Peptides. XXI. Laminin-Related Peptide Analogs Including Poly(Ethylene Glycol) Hybrids and Their Inhibitory Effect on Experimental Metastasis
- PREPARATION OF [ARG-GLY-ASP]-[AMINO-POLY(ETHYLENE GLYCOL)] HYBRIDS AND THEIR INHIBITORY EFFECT ON EXPERIMENTAL METASTASIS
- Amino Acids and Peptides. XXIV. Preparation and Antinociceptive Effect of [D-Ala^2,(N-Me)Phe^4]Enkephalin Analog-Poly(Ethylene Glycol)Hybrids
- Amino Acids and Peptides. XXIII. Leu-Enkephalin Analogs Containing a Fluorinated Amino Acid at Position 2,4 or 5
- Human Chorionic Gonadotropin. VII. Preparation and Immunocharacteristics of Carboxyl-terminal Peptides of the β-Subunit of Human Chorionic Gonadotropin
- Human Chorionic Gonadotropin. VI. Synthesis of a Tetratriacontapeptide corresponding to the C-Terminal Sequence 112-145 of the β-Subunit of Human Chorionic Gonadotropin (hCG)
- Human Chorionic Gonadotropin. V. Synthesis of a Triacontapeptide corresponding to the C-Terminal Sequence 116-145 of the β-Subunit of Human Chorionic Gonadotropin (hCG)
- Human Chorionic Gonadotropin. IV. Synthesis of a Hexadecapeptide corresponding to the C-Terminal Sequence 130-145 of the β-Subunit of Human Chorionic Gonadotropin (hCG)
- Human Chorionic Gonadotropin. III. Synthesis of a Dotriacontapeptide corresponding to the C-Terminal Sequence 116-147 of the β-Subunit of Human Chorionic Gonadotropin (hCG)
- Human Chorionic Gonadotropin. II. Synthesis of a Hexadecapeptide corresponding to the C-Terminal Sequence 132-147 of the β-Subunit of Human Chorionic Gonadotropin (hCG)
- Synthesis of C-Terminal Peptides of the β-Subunit of Human Chorionic Gonadotropin (hCG)
- 生理活性ペプチドの高分子ハイブリッド化 DDS - ポリスチレンマレイン酸によるラミニン関連細胞接着ペプチドのバイオコンジュゲーションとその癌転移抑制効果 -
- Amino Acids and Peptides. XXII. Preparation and Antinociceptive Effect of [D-Ala^2] Leu-Enkephalin-Poly (Ethylene Glycol) Hybrid
- Amino Acids and Peptides. XIX. Preparation of Enkephalin-Poly(ethylene glycol) Hybrid and Evaluation of Its Analgesic Activity
- Amino Acids and Peptides. XVII. Synthesis of Peptides Related to N-Terminal Portion of Fibrin α-Chain and Their Inhibitory Effect on Fibrinogen : Thrombin Clotting
- Synthesis of a Tetradecapeptide corresponding to Sequence 90-103 of Bovine Adrenodoxin
- Amino Acids and Peptides. I. Synthesis of a Model Peptide related to Iron-Sulfur Protein
- Synthesis of Two Heptapeptides corresponding to Sequences 50-56 and 90-96 of Adrenodoxin from Bovine Adrenal Cortex and Formation of Their Iron-Sulfur Complexes
- Studies on Peptides. XVI. Regeneration of Lysine from N^ε-Formyllysine by Aqueous Hydrazine or Hydroxylamine and Their Application to the Synthesis of α-Melanocyte-stimulating Hormone
- Preparation and Biological Activities of a Bivalent Poly(Ethylene Glycol) Hybrid Containing an Active Site and Its Synergistic Site of Fibronectin
- Synthesis of a Tetradecapeptide corresponding to Sequence 50-63 of Adrenodoxin from Bovine Adrenal Cortex and Formation of Its Iron-Sulfur Complex
- Facile Conversions of Carboxylic Acids into Amides, Esters, and Thioesters Using 1,1'-Oxalyldiimidazole and 1,1'-Oxalyldi(1,2,4-triazole)(Organic,Chemical)
- Amino Acids and Peptides. X. : Leu-Enkephalin Analogues Containing a Fluorinated Aromatic Amino Acid
- Amino Acids and Peptides. IX. : Synthetic Studies on Leu-Enkephalin Analogues Containing a Ureylene Bond
- Amino Acids and Peptides. VI. Synthesis of the N-Terminal Pentapeptide of α_2-Plasmin Inhibitor and Its Analogue
- Effects of α-Linolenic Acid-rich Diacylglycerol on Diet-induced Obesity in Mice
- Effects of Tea Catechins on Diet-induced Obesity in Mice〔和文〕
- Enhancing Effect of α-Monoisostearyl Glyceryl Ether on the Percutaneous Penetration of Indomethacin through Excised Rat Skin
- Studies on Heterobifunctional Cross-Linking Reagents, 6-Maleimidohexanoic Acid Active Esters
- "Solid Phase Synthesis in Water" Using Fmoc-Amino Acid Nanoparticles
- Amino Acids and Peptides.XXXVIII.Facile Synthesis of Laminin-Related Peptide-Poly(Ethylene Glycol)Hybrids by the Solid Phase Method
- Studies on α_2-Plasmin Inhibitor Fragment T-11. III. Structure-Activity Relationships among the Fragments of T-11, the Plasminogen Binding Site(s) of Human α_2-Plasmin Inhibitor(Medicinal Chemistry,Chemical)
- Medicinal Chemical Studies on Antiplasmin Drugs. I. Establishment of the Screening Assay Method for Antiplasmin Drugs and the Superiority of trans-4-Aminomethylcyclohexanecarboxylic Acid (Tranexamic Acid) to cis-Form
- Conjugation of a Laminin-Related Antimetastatic Peptide with Chitosan (Part 3)
- Synthesis of Peptide Mimetics That Related to Tethered Thrombin Receptor and Their Agonist/Antagonist Activities on Platelet Aggregation
- Evaluation of a New N-Protecting Group, 2-(4-Sulfophenylsulfonyl)ethoxycarbonyl Group, for Solid Phase Peptide Synthesis in Water
- Peptide Synthesis in Water IV. Preparation of N-Ethanesulfonylethoxycarbonyl (Esc) Amino Acids and Their Application to Solid Phase Peptide Synthesis
- Solid Phase Synthesis in Water : Application of the Ethanesulfonylethoxycaronyl (Esc) Group
- Improved Preparation of an Amino Acid Type Poly(Ethylene Glycol) Derivative
- A New N-Protecting Group, 2-[Phenyl(methyl)sulfonio]ethyloxycarbonyl Tetrafluoroborate, and Its Application to Solid Phase Peptide Synthesis in Water
- Acylation of Hydrazides with Acetic Acid and Formic Acid
- A Bivalent Poly (ethylene glycol) Hybrid Containing an Active Site (RGD) and a Synergistic Site of Fibronectin
- Amino Acids and Peptides. XXXV. Facile Preparation of p-Nitroanilide Analogs by the Solid-Phase Method
- A Facile Solid-Phase Synthesis of Peptide ρ-Nitroanilide Analogs
- Regioselective Conjugation of Chitosan with a Laminin-related Peptide, Tyr-Ile-Gly-Ser-Arg, and Evaluation of Its Inhibitory Effect on Experimental Cancer Metastasis
- Synthesis of Some Pseudo-Peptide Analogs of Thiol Proteinase Inhibitors
- Amino Acids and Peptides. VIII. : A Water-Soluble Active Ester, Phenolsulfonic Acid Derivative(Organic,Chemical)
- Studies on Peptides XVIII. Catalytic Hydrogenation of Methionine-containing Peptides
- The Use of Boron Trifluoride Etherate for Debenzyloxycarbonylation of Methionine-containing Peptides by Catalytic Hydrogenolysis
- Amino Acids and Peptides. XX. Preparation of β-Cyclododecyl Aspartate and Its Application to Synthesis of Fibronectin- and Laminin-Related Peptides
- Amino Acids and Peptides. XI. : Simple Preparation of N^α-Protected Histidine
- Preparation of Laminin γ1 Chain Related Peptide Poly (Ethylene Glycol) Hybrid
- Amino Acids and Peptides. XXXI. Preparation of Analogs of the Laminin-Related Peptide YIGSR and Their Inhibitory Effect on Experimental Metastasis
- Amino Acids and Peptides. XXX. Preparation of Arg-Gly-Asp (RGD) Hybrids with Poly(Ethylene Glycol) Analogs and Their Antimetastatic Effect
- Amino Acids and Peptides. XXIX. Synthesis and Antimetastatic Effects of Peptides and Peptide-Poly(Ethylene Glycol) Hybrids Related to the Core Sequence of the Type III Connecting Segment Domain of Fibronectin
- Studies on Peptides. XXVIII. Synthesis of the Docosapeptide which Embodies the Entire Amino Acid Sequence of β-Melanocyte-stimulating Hormone from Human Pituitary Gland
- Amino Acids and Peptides. XXVII. Solid Phase Synthesis of Fibrinogen-Related Peptides with Disulfide Bond Formed on Solid Support
- Preparation of Laminin-related Peptide Analogs and Their Inhibitory Effect on Experimental Metastasis in Mice
- Amino Acids and Peptides. XVI. Synthesis of N-Terminal Tetrapeptide Analogs of Fibrin α-Chain and Their Inhibitory Effects on Fibrinogen : Thrombin Clotting
- Amino Acids and Peptides. XIII. Synthetic Studies on N-Terminal Tripeptide Amide Analogs of Fibrin α-Chain
- Amino Acids and Peptides. V. Synthesis of Amino Acid Derivatives Containing a Sulfonamide Bond
- Amino Acids and Peptides. XXVIII. Preparation of Poly(Ethylene Glycol)Hybrids of Gln-Val-Val-Ala-Gly Analogs and Their Inhibitory Effect on Papain
- Preparation of A Fibronectin-related Poly(Ethylene Glycol) Hybrid and Its Inhibitory Effect on Experimental Metastasis in Mice
- Amino Acids and Peptides. III. Synthesis of Model Peptides Related to Cytochrome P-450
- Amino Acids and Peptides. XVIII. Synthetic Peptides Related to N-Terminal Portion of Fibrin α-Chain and Their Inhibitory Effect on Fibrinogen/Thrombin Clotting
- The Opioid Activity and Receptor Selectivity of Fluorinated Leu^5 Enkephalin Analogues in Vitro and in Vivo
- Selectivity for Opioid Receptor Subtypes of Enkephalin Analogues in Isolated Smooth Muscle and in the Analgesic Effect in Mice
- INVOLVEMENT OF DIFFERENT RECEPTOR SUBTYPES FOR THE PRODUCTION OF IN VITRO AND IN VIVO EFFECTS IN A SERIES OF SYNTHETIC ENKEPHALIN ANALOGUES
- Microwave Assisted Solid-Phase Peptide Synthesis in Water Using Water-Dispersible Fmoc-Amino Acid NanoParticles
- プリオンタンパク質の銅結合部位
- ラミニン由来ガン転移抑制ペプチドとキトサンとのハイブリッド体の調製
- Studies on Peptides. IX. Synthesis of N-(Histidylphenylalanylarginy1)-5-methoxytryptamine, an Inhibitor of α-Melanocyte-stimulating Hormone in virto
- Studies on Peptides. XIX. Synthesis of a Stereoisomer of α-Melanocyte-stimulating Hormone
- Studies on Peptides. XVII. Synthesis of N-(N^α-Acetylseryltyrosylserylmethionylglutamylhistidylphenylalanylarginyl)-5-methoxy-tryptamine and Its Physiological Properties on Frog Melanocyte in vitro