Amino Acids and Peptides. V. Synthesis of Amino Acid Derivatives Containing a Sulfonamide Bond
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概要
- 論文の詳細を見る
Amino acid derivatives containing a sulfonamide bond were synthesized and their biological activities were examined. Some sulfonyllysine derivatives exhibited fibrinolytic activity. N^4-Lysylsulfanilamide was also prepared and treated with trypsin. The results suggest that a drug acylated with an amino acid might have improved solubility in water and might act as a kind of prodrug.
- 公益社団法人日本薬学会の論文
- 1985-05-25
著者
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川崎 紘一
Faculty of Pharmaceutical Sciences, Kobe Gakuin University
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前田 光子
Faculty of Pharmaceutical Sciences, Kobe Gakuin University
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Maeda M
Department Of Pharmacology Faculty Of Pharmaceutical Sciences Nagasaki University:faculty Of Pharmac
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岡田 裕
Faculty Of Pharmaceutical Sciences Kobe-gakuin University
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曽我部 真紀
Faculty of Pharmaceutical Sciences, Kobe-Gakuin University
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Kawasaki Keiko
Biological Science Laboratories Kao Corporation
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川崎 紘一
Faculty Of Pharmaceutical Sciences & Cooperative Research Center Of Life Sciences Kobe Gakuin Un
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Maeda Masatomo
Laboratory Of Biochemistry And Molecular Biology Graduate School Of Pharmaceutical Sciences Osaka Un
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曽我部 真紀
Faculty Of Pharmaceutical Sciences Kobe-gakuin University
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