Amino Acids and Peptides. IX. Synthesis of Cysteine-Containing Peptide Fragments Related to Human Hepatic Metallothionein II (hMT II) and Determination of Their Heavy Metal-Binding Properties
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概要
- 論文の詳細を見る
Eight kinds of cysteine-containing peptides related to human hepatic metallothionein were synthesized by conventional methods. The metal-binding properties of these peptides with Zn^<2+> and Cd^<2+> were indicated by an increase of ultraviolet absorbance resulting from mercaptide formation. The Cd-binding activities of various peptides obtained here were assessed by measuring the increase in absorbance of mercaptide at 250 nm as a function of the concentration of Cd. The binding abilities of the peptides with Cd differed substancially.
- 公益社団法人日本薬学会の論文
- 1983-09-25
著者
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岡田 芳男
Faculty of Pharmaceutical Sciences Kobe-Gakuin University
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田中 慶一
Faculty of Nutrition , Kobe-Gakuin University
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大田 憲哉
Faculty of Pharmaceutical Sciences
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大田 憲哉
Hitachi Chemical Co. Ltd. Ibaraki Research Laboratory
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