Antifungal Activity against Plant-Pathogenic Fungi and Phytogrowth-Inhibitory Activity of 3,3'-Dihydroxy-α, β-diethyldiphenylethane

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概要

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• 3,3'-Dihydroxy-α, β-diethyldiphenylethane (I), an isomer of hexestrol (IV), showed antifungal activity against plant-pathogenic fungi and phytogrowth-inhibitory activity. First, compound I had antifungal activity against all plant-pathogenic fungi examined. The antifungal spectrum of I was similar to those of IV, diethylstilbestrol (III) and 3,3'-dihydroxy-α, β-diethylstilbene (II). However, compound I, unlike II, III and IV, showed antifungal activity against Ceratocystis fimbriata IFO-4864. Next, compound I strongly inhibited the growth of roots of two plant species even at the low concentration of 50 ppm. The inhibitory effect of I was as strong as that of sodium 2,4-dichlorophenoxyacetate used as a standard.It is noteworthy that compound I, in spite of the loss of hormonal side effect, retained the above-mentioned activities.

• 社団法人日本薬学会の論文
• 1988-08-25

著者

• 竹村 庄司

  Faculty Of Pharmaceutical Sciences Kinki University

• 稲森 善彦

  Osaka University of Pharmaceutical Sciences

• 辻坊 裕

  Osaka University of Pharmaceutical Sciences

• 小川 雅史

  Osaka University Of Pharmaceutical Sciences

• 三木 康義

  Faculty of Pharmaceutical Sciences, Kinki University

• 辻坊 裕

  大阪薬大

• 三木 康義

  Faculty Of Pharmaceutical Sciences Kinki University

• 三木 康義

  近畿大学 薬学部

• 竹村 庄司

  Faculty of Pharmaceutical Sciences, Kinki University

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