THE ICHTHYOTOXICITY AND CORONARY VASODILATOR ACTION OF DIETHYLSTILBESTROL

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概要

• 論文の詳細を見る

• Diethylstilbestrol (I), a nonsteroidal estrogen, showed strong ichthyotoxicity and coronary vasodilator action on isolated guineapig hearts. The median ichthyotoxicity tolerance limit (TLm) at 48 h was 3.30 ppm in Oryzias latipes TEMMINCK et SCHLEGEL and 4.50 ppm in Carassius auratus LINNE. The vasodilator activity of I in isolated guinea-pig hearts (ED_<50> : 0.26 μg/heart) was much stronger than that of papaverine (7.0 μg/heart) used as a standard.

• 社団法人日本薬学会の論文
• 1985-01-25

著者

• 稲森 善彦

  Osaka University of Pharmaceutical Sciences

• 馬場 きみ江

  Osaka University of Pharmaceutical Sciences

• 辻坊 裕

  Osaka University of Pharmaceutical Sciences

• 小澤 貢

  Osaka University of Pharmaceutical Sciences

• 小川 雅史

  Osaka University Of Pharmaceutical Sciences

• 久保 真百合

  Osaka University of Pharmaceutical Sciences

• 森脇 将光

  Osaka College of Pharmacy

• 辻坊 裕

  大阪薬大

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