Effects of Stilbene Components of the Roots of Polygonum cuspidatum SIEB. et ZUCC. on Lipid Metabolism
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概要
- 論文の詳細を見る
The effects of the roots of Polygonum cuspidatum SIEB. et ZUCC. ("Kojo-kon" or "Itadori-kon" in Japanese) and its stilbene components (resveratrol and piceid) on lipid metabolism in rats and mice (higher animals) were investigated. Resveratrol and piceid inhibited the deposition of triglyceride and cholesterol in the liver of rats fed corn oil-cholesterol-cholic acid mixture. Piceid reduced the serum triglyceride and low density lipoprotein-cholesterol (LDL-ch) levels, and atherogenic index [total cholesterolhigh density lipoprotein-cholesterol (HDL-ch)/HDL-ch] in the oil mixture-fed rats. It was found that intraperitoneal or oral administration of resveratrol or piceid reduced triglyceride synthesis from ^<14>C-palmitate in the liver of mice. In contrast, these stilbene components did not affect hormone-induced lipolysis in fat cells from rat eqididymal adipose tissue.
- 公益社団法人日本薬学会の論文
- 1982-05-25
著者
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小澤 貢
Osaka University of Pharmaceutical Sciences
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木村 善行
愛媛大学大学院医学系研究科統合医科学講座薬理生化学分野
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有地 滋
The Research Institute of Oriental Medicine, Kinki University
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有地 滋
The Research Institute Of Oriental Medicine Kinki University
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有地 滋
近畿大学東洋医学研究所
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奥田 拓道
愛媛大学
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奥田 拓道
2nd Department of Medical Biochemistry, School of Medicine, Ehime University
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有地 滋
愛媛大学
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