Studies on Scutellariae Radix. V. Effects on Ethanol-induced Hyperlipemia and Lipolysis in Isolated Fat Cells
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概要
- 論文の詳細を見る
The effects of oral administration of flavonoid components of Scutellariae Radix on serum and liver lipid levels of rats treated with ethanol were investigated. It was found that wogonin reduced serum triglyceride level, and that baicalein and baicalin, the major components of the drug, decreased total cholesterol, free cholesterol and triglyceride contents in the liver. Baicalein increased high density lipoprotein-cholesterol (HDL-ch) in the serum of the ethanol-treated rats. In addition to these in vivo experiments, the actions of wogonin, baicalein and baicalin on catecholamine-induced lipolysis in isolated fat cells were investigated. It was found that the three flavones inhibited noradrenaline-induced lipolysis in isolated fat cells. The relationship between these in vivo and in vitro experiments is discussed.
- 公益社団法人日本薬学会の論文
- 1982-01-25
著者
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木村 善行
愛媛大学大学院医学系研究科統合医科学講座薬理生化学分野
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久保 道徳
Faculty Of Pharmaceutical Sciences Kinki University
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谿 忠人
The Research Institute of Oriental Medicine, Kinki University
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有地 滋
The Research Institute of Oriental Medicine, Kinki University
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有地 滋
The Research Institute Of Oriental Medicine Kinki University
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東野 正行
Nippon Funmatsu Yakuhin Co., Ltd.
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有地 滋
近畿大学東洋医学研究所
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奥田 拓道
愛媛大学
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奥田 拓道
2nd Department of Medical Biochemistry, School of Medicine, Ehime University
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木村 善行
2nd Department of Medical Biochemistry, School of Medicine, Ehime University
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有地 滋
愛媛大学
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谿 忠人
近畿大学東洋医学研究所・第1研究部門
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東野 正行
Nippon Funmatsu Yakuhin Co. Ltd.
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草加 君代
Faculty of Pharmaceutical Sciences, Kinki University
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東野 正行
The Research Institute of Oriental Medicine, Kinki University
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草加 君代
Faculty Of Pharmaceutical Sciences Kinki University
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