Anti-thrombic Actions of 70% Methanolic Extract and Cinnamic Aldehyde from Cinnamomi Cortex(Pharmacognosy,Chemical)
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概要
- 論文の詳細を見る
The anti-thrombic activities of a 70% methanolic extract (CMe) from Cinnamomi Cortex on blood coagulation and fibrinolysis were investigated. CMe prevented the hepatic venous thrombosis in high butter diet-treated rats, and the decreases of blood platelets and fibrinogen in normal rats induced by endotoxin. CMe also inhibited the blood platelet aggregation induced by collagen, arachidonic acid and adenosine diphosphate (ADP) and the conversion of fibrinogen to fibrin induced by thrombin in in vitro experiments. Cinnamic aldehyde, a major essential oily component of CMe were showed stronger inhibitory activity than that of CMe on the blood coagulation. These results suggest that Cinnamomi Cortex has anti-throrabic activities.
- 社団法人日本薬学会の論文
- 1987-03-25
著者
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塩本 秀己
大正製薬株式会社セルフメディケーション開発研究所
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久保 道徳
Faculty Of Pharmaceutical Sciences Kinki University
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塩本 秀己
Faculty of Pharmaceutical Sciences, Kinki University
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松田 玲子
Faculty of Pharmaceutical Sciences, Kinki University
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福田 誠也
Faculty of Pharmaceutical Sciences, Kinki University
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福田 誠也
Faculty Of Pharmaceutical Sciences Kinki University
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松田 玲子
Faculty Of Pharmaceutical Sciences Kinki University
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