Studies of Anti-cataract Drugs from Natural Sources. I. Effects of a Methanolic Extract and the Alkaloidal Components from Corydalis Tuber on in Vitro Aldose Reductase Activity
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概要
- 論文の詳細を見る
The inhibitory effect of Corydalis tuber (Corydalis turtschaninovii BESSER forma yanhusuo Y. H. CHOU et C. C. HSU) was tested on crude rat lens aldose reductase, an enzyme involved in the complications of diabetes. The methanolic extract (CM-ext) inhibited aldose reductase, while the aqueous extract (CA-ext) was ineffective. Only dehydrocorydaline, of the seven alkaloidal components isolated from CM-ext, inhibited aldose reductase. It is suggested that the inhibitory effect of CM-ext on aldose reductase may be partially attributed to dehydrocorydaline.
- 社団法人日本薬学会の論文
- 1994-03-15
著者
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田中 孝幸
Daiichi Seiyaku Co. Ltd.
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松田 秀秋
Faculty of Pharmaceutical Sciences,Kinki University
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久保 道徳
Faculty Of Pharmaceutical Sciences Kinki University
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徳岡 清司
Faculty Of Pharmaceutical Sciences Kinki University
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Tokuoka Kiyoshi
Faculty Of Pharmaceutical Sciences Kinki University
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馬 世平
Faculty Of Pharmaceutical Sciences Kinki University
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小林 由佳
Faculty of Pharmaceutical Sciences, Kinki University
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Tanaka T
Graduate School Of Biomedical Sciences Nagasaki University
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Tanaka T
School Of Pharmaceutical Sciences Nagasaki University
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松田 秀秋
Faculty Of Pharmaceutical Sciences Kinki University
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Tanaka T
Tohoku Univ. Sendai Jpn
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Tanaka Takemi
School Of Agriculture Kyushu Tokai University
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小林 由佳
Faculty Of Pharmaceutical Sciences Kinki University
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