Structures of Epicatechin Gallate Trimer and Tetramer Produced by Enzymatic Oxidation
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概要
- 論文の詳細を見る
During black tea production, catechins and their galloyl esters are enzymatically oxidized to generate a complex mixture of black tea polyphenols. The role of galloyl ester groups in this process has yet to be determined. Enzymatic oxidation of epicatechin 3-O-gallate (1) yielded two new oxidation products, theaflavate C and bistheaflavate A, along with theaflavate A (2), a known dimer of 1 generated by coupling of the B-ring with the galloyl group. Theaflavate C is a trimer of 1 and possesses two benzotropolone moieties generated by the oxidative coupling of the galloyl groups with the catechol B-rings. Bistheaflavate A was found to be a tetramer produced by intermolecular coupling of two benzotropolone moieties of 2. From the structures of the products, it was deduced that oxidative coupling of galloyl groups resulted in extension of the molecular size of the products in catechin oxidation.
- 公益社団法人日本薬学会の論文
- 2007-12-01
著者
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田中 隆
長崎大学大学院医歯薬学総合研究科
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田中 隆
長崎大 大学院医歯薬学総合研究科
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Tanaka Takashi
Graduate School Of Education Hiroshima University
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松尾 洋介
長崎大学大学院医歯薬学総合研究科
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Matsuo Yosuke
Graduate School Of Biomedical Sciences Nagasaki University
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Matsuo Yosuke
Graduate School Of Biomedical Sciences Nagasaki Univ.
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KOUNO Isao
Graduate School of Biomedical Sciences, Nagasaki University
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Kouno I
Nagasaki Univ. Nagasaki Jpn
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Kouno Isao
Graduate School Of Biomedical Sciences Nagasaki University
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Kouno Isao
Course Of Pharmaceutical Sciences Graduate School Of Biomedical Sciences Nagasaki University
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Kouno Isao
Graduate School Of Biomedical Sciences Nagasaki Univ.
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Tanaka Tomonori
Faculty Of Medical And Pharmaceutical Sciences Kumamoto University
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KUSANO Rie
Graduate School of Biomedical Sciences, Nagasaki University
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田中 隆
Faculty Of Pharmaceutical Sciences Kyushu University
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Tanaka T
School Of Pharmaceutical Sciences Nagasaki University
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Kusano Rie
Graduate School Of Biomedical Sciences Nagasaki University
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Tanaka Takemi
School Of Agriculture Kyushu Tokai University
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Tanaka T
Fukuyama Univ. Hiroshima Jpn
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Tanaka Takashi
Graduate School Of Biomedical Sciences Nagasaki University
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Tanaka Takashi
Graduate School Of Biochemical Science Nagasaki University
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Kouno Isao
Graduate School of Biomedical Sciences and School of Pharmaceutical Sciences, Nagasaki University
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