Rubusuaviins A-F, Monomeric and Oligomeric Ellagitannins from Chinese Sweet Tea and Their α-Amylase Inhibitory Activity
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概要
- 論文の詳細を見る
Six new ellagitannins herein, rubusuaviins A?F, were isolated from the aqueous acetone extract of Chinese sweet tea (Tien-cha, dried leaves of Rubus suavissimus S. LEE) together with seven known tannins. Rubusuaviin A was characterized as 1-O-galloyl-2,3-O-(S)-HHDP-4,6-O-(S)-sanguisorboyl-β-D-glucopyranose. Rubusuaviins B, C, and E are dimeric, trimeric, and tetrameric ellagitannins, respectively, in which the sanguisorboyl groups were connected ellagitannin units. Rubusuaviins D and F were desgalloyl derivatives of rubusuaviins C and E, respectively. The inhibition of α-amylase activity by rubusuaviins and related ellagitannins was compared. Ellagitannins with β-galloyl groups at the glucose C-1 positions showed stronger inhibition compared with the α-galloyl and desgalloyl compounds. The molecular weight of these compounds was not important for the inhibition of α-amylase activity.
- 社団法人日本薬学会の論文
- 2007-09-01
著者
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田中 隆
長崎大学大学院医歯薬学総合研究科
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田中 隆
長崎大 大学院医歯薬学総合研究科
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Tanaka Takashi
Graduate School Of Education Hiroshima University
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Yang C‐r
Laboratory Of Phytochemistry Kunming Institute Of Botany Chinese Academy Of Sciences
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Zhang Y‐j
Laboratory Of Phytochemistry Kunming Institute Of Botany Chinese Academy Of Sciences
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LI Haizhou
Graduate School of Biomedical Sciences, Nagasaki University
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ZHANG Ying-Jun
Laboratory of Phytochemistry, Kunming Institute of Botany, Chinese Academy of Sciences
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YANG Chong-Ren
Laboratory of Phytochemistry, Kunming Institute of Botany, Chinese Academy of Sciences
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KOUNO Isao
Graduate School of Biomedical Sciences, Nagasaki University
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Li Haizhou
Graduate School Of Biomedical Sciences Nagasaki University
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Li Haizhou
長崎大学 医歯薬総合研究科
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Kouno I
Nagasaki Univ. Nagasaki Jpn
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Kouno Isao
Graduate School Of Biomedical Sciences Nagasaki University
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Kouno Isao
Course Of Pharmaceutical Sciences Graduate School Of Biomedical Sciences Nagasaki University
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Yang Chong-ren
Laboratory Of Phytochemistry Kunming Institute Of Botany Chinese Academy Of Science
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Kouno Isao
Graduate School Of Biomedical Sciences Nagasaki Univ.
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Tanaka Tomonori
Faculty Of Medical And Pharmaceutical Sciences Kumamoto University
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Zhang Ying-jun
Laboratory Of Phytochemistry Kunming Institute Of Botany Chinese Academy Of Sciences
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田中 隆
Faculty Of Pharmaceutical Sciences Kyushu University
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Tanaka T
School Of Pharmaceutical Sciences Nagasaki University
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Tanaka Takemi
School Of Agriculture Kyushu Tokai University
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Tanaka T
Fukuyama Univ. Hiroshima Jpn
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Tanaka Takashi
Graduate School Of Biomedical Sciences Nagasaki University
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Tanaka Takashi
Graduate School Of Biochemical Science Nagasaki University
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Kouno Isao
Graduate School of Biomedical Sciences and School of Pharmaceutical Sciences, Nagasaki University
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