Studies on the Activities of Tannins and Related Compounds of Medicinal Plants and Drugs. III. Effects of Various Tannins and Related Compounds on Adrenocorticotropic Hormon-induced Lipolysis and Insulin-induced Lipogenesis from Glucose in Fat Cells. (2)

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概要

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• The effects of various tannins and related compounds on the actions of adrenocorticotropic hormone (ACTH) and insulin in fat cells isolated from rats were investigated. Hydrolyzable tannins such as geraniin, mallotusinic acid, chebulinic acid and chebulagic acid enhanced the ACTH-induced lipolysis at the concentration of 20 μg/ml or 5 μg/ml. On the other hand, these hydrolyzable tannins had no effect on the insulin-stimulated lipogenesis from glucose. Condensed tannins such as Ss-tannin 1 and RSF-tannin H showed weak inhibitory effects on the ACTH-induced lipolysis, while they enhanced the insulin-stimulated lipogenesis from glucose. Based on these results, the relationship between the structures and physiological actions of these tannins is discussed.

• 公益社団法人日本薬学会の論文
• 1983-07-25

著者

• 吉田 隆志

  Faculty of Pharmaceutical Sciences, Okayama University

• 奥田 拓男

  Faculty of Pharmaceutical Sciences, Okayama University

• 吉田 隆志

  Department Of Pharmacognosy College Of Pharmaceutical Sciences Matsuyama University

• 波多野 力

  Faculty of Pharmaceutical Sciences, Okayama University

• 木村 善行

  愛媛大学大学院医学系研究科統合医科学講座薬理生化学分野

• 奥村 智子

  Faculty Of Pharmaceutical Sciences Okayama University

• 有地 滋

  The Research Institute of Oriental Medicine, Kinki University

• 有地 滋

  The Research Institute Of Oriental Medicine Kinki University

• 有地 滋

  近畿大学東洋医学研究所

• 奥田 拓道

  愛媛大学

• 奥田 拓道

  熊本県立大学環境共生学部環境共生学科食健康環境学科

• 奥田 拓道

  2nd Department of Medical Biochemistry, School of Medicine, Ehime University

• Kiso Yoshinobu

  Institute For Biomedical Research Suntory Ltd.

• 奥田 拓男

  Faculty Of Parmaceutical Sciences University

• 木村 善行

  2nd Department of Medical Biochemistry, School of Medicine, Ehime University

• 有地 滋

  愛媛大学

• 吉田 隆志

  Faculty Of Pharmaceutical Sciences Kyoto University

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