Enzymatic Sulfation of isoamyl Gallate and (-)-Epigallocatechin Gallate by Bacterial Arylsulfotransferase
スポンサーリンク
概要
- 論文の詳細を見る
A novel type of arylsulfotransferase which was obtained from a human intestinal bacterium catalyzes the sulfation of polyphenols related to tannins. Isoamyl gallate and (-)-epigallocatechin gallate were found to be sulfated rapidly using p-nitrophenylsulfate as a donor substrate. In the case of isoamyl gallate, two sulfated products, 3-monosulfate and 4-monosulfate, were isolated when an equimolar amount of p-nitrophenylsulfate was incubated with isoamyl gallate. In the case of (-)-epigallocatechin gallate. 4'-monosulfate was isolated at an equimolar incubation of donor and acceptor. Thus, arylsulfotransferase was useful for the convenient preparation of sulfate esters of these polyphenols.
- 社団法人日本薬学会の論文
- 1992-07-25
著者
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吉田 隆志
Faculty of Pharmaceutical Sciences, Okayama University
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奥田 拓男
Faculty of Pharmaceutical Sciences, Okayama University
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吉田 隆志
Department Of Pharmacognosy College Of Pharmaceutical Sciences Matsuyama University
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小橋 恭一
Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceutical University
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土肥 啓司
Faculty of Pharmaceutical Sciences Toyama Medical and Pharmaceutical University
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赤尾 光昭
富山医科薬科大学薬学部
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小橋 恭一
富山医科薬科大学
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今村 理佐
Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University
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赤尾 光昭
Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University
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古泉 素明
Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University
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奥村 智子
Faculty Of Pharmaceutical Sciences Okayama University
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奥田 拓男
Takeda Chemical Ind. Ltd. Osaka Jpn
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今村 理佐
Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceutical University
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小橋 恭一
富山医薬大薬学部
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奥田 拓男
Faculty Of Parmaceutical Sciences University
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吉田 隆志
Faculty Of Pharmaceutical Sciences Kyoto University
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古泉 素明
Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceutical University
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