Carbonic Anhydrase Inhibitors from the Pericarps of Punica granatum L.
スポンサーリンク
概要
- 論文の詳細を見る
Seven highly active inhibitors against carbonic anhydrase (CA, EC 4.2.1.1), punicalin (2), punicalagin (3), granatin B (5), gallagyldilactone (7), casuarinin (8), pedunculagin (9) and tellimagrandin I (10), and four weakly active inhibitors, gallic acid (1), granatin A (4), corilagin (6) and ellagic acid (11), were isolated from the pericarps of Punica granatum L. (Punicaceae). They are ellagitannins. The type of inhibition by 3 and 7 using p-nitrophenyl acetate as a substrate, is noncompetitive. The structure-activity relationship of inhibitory effects on CA is discussed.
- 公益社団法人日本薬学会の論文
- 1993-08-15
著者
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上野 明
School Of Pharmaceutical Sciences University Of Shizuoka
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奥田 拓男
Faculty of Pharmaceutical Sciences, Okayama University
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波多野 力
Faculty of Pharmaceutical Sciences, Okayama University
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Hatano Tsutomu
エジプト
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Hatano Tsutomu
Division Of Pharmaceutical Sciences Okayama University Graduate School Of Medicine Dentistry And Pha
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野呂 忠敬
Graduate School Of Nutritional And Environmental Sciences University Of Shizuoka
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野呂 忠敬
静岡県立大学
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奥村 智子
Faculty Of Pharmaceutical Sciences Okayama University
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奥田 拓男
Takeda Chemical Ind. Ltd. Osaka Jpn
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上野 明
School Of Pharmaceutical Science University Of Shizuoka
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奥田 拓男
Faculty Of Parmaceutical Sciences University
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里見 勇人
School of Pharmaceutical Sciences, University of Shizuoka
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梅村 敬治郎
School of Pharmaceutical Sciences, University of Shizuoka
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梅村 敬治郎
School Of Pharmaceutical Sciences University Of Shizuoka
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里見 勇人
School Of Pharmaceutical Sciences University Of Shizuoka
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