Studies on Dental Caries Prevention by Traditional Medicines. VIII. : Inhibitory Effect of Various Tannins on Glucan Synthesis by Glucosyltransferase from Streptococcus mutans
スポンサーリンク
概要
- 論文の詳細を見る
Hydrolyzable tannins from crude drugs were examined for inhibitory activity against glucosyltransferase from a cariogenic bacterium, Streptococcus mutans. Pentagalloylglucose showed a strong inhibitory effect, whereas ellagitannins stimulated the glucan synthesis in 10% ethanol. All the gallotannins were more potent than chlorhexidine gluconate in an aqueous reaction mixture. Among them, penta- and hexagalloylglucose were the most potent, being inhibitory at a concentration of 10^<-3>M. The inhibitory character of gallotannins depended on the number of galloyl residues.
- 社団法人日本薬学会の論文
- 1986-02-25
著者
-
奥田 拓男
Faculty of Pharmaceutical Sciences, Okayama University
-
服部 征雄
富山医科薬科大学和漢薬研究所
-
服部 征雄
Research Institute for Wakan-Yaku, Toyama Medical and Pharmaceutical University
-
難波 恒雄
Research Institute for Wakan-Yaku (Oriental Medicines), Toyama Medical and Pharmaceutical University
-
山岸 喬
北見工業大学
-
山岸 喬
Hokkaido Institute Of Public Health
-
西澤 信
共成製薬(株)
-
西沢 信
北海道立衛生研究所
-
西沢 信
Hokkaido Institute of Public Health
-
垣内 信子
Research Institute for Wakan-Yaku (Oriental Medicines), Toyama Medical and Pharmaceutical University
-
奥田 拓男
Faculty Of Parmaceutical Sciences University
-
奥田 拓男
Faculty Of Pharmaceutical Sciences Kyoto University
-
西沢 信
共成製薬(株)
-
垣内 信子
Research Institute For Wakan-yaku (traditional Sino-japanese Medicines) Toyama Medical And Pharmaceu
-
服部 征雄
Research Institute For Wakan-yaku (oriental Medicines) Toyama Medical And Pharmaceutical University
-
難波 恒雄
Research Institute For Wakan-yaku (oriental Medicines) Toyama Medical And Pharmaceutical University
関連論文
- Tannins and Related Polyphenols of Euphorbiaceous Plants. IX. Hydrolyzable Tannins with ^1C_4 Glucose Core form Phyllanthus flexuosus MUELL. ARG.
- I-A-10 5/6 腎摘ラットにおける丹参成分 lithospermic acid B Mg 塩投与効果の検討 (1)
- II-A-16 丹参成分 Lithospermic acid B Mg 塩の血圧下降作用
- I-B-16 大黄成分の hydroxyl radical scavenger 作用 : 腎不全惹起ラットを用いた場合
- I-B-16 大黄成分の hydroxyl radical scavenger 作用 : 腎不全惹起ラットを用いた場合
- Woodfordin C, a Macro-ring Hydrolyzable Tannin Dimer with Antitumor Activity, and Accompanying Dimers from Woodfordia fruticosa Flowers
- CAMELLIIN B AND NOBOTANIN I, MACROCYCLIC ELLAGITANNIN DIMERS AND RELATED DIMERS, AND THEIR ANTITUMOR ACTIVITY
- Relationship between the Structures and the Antitumor Activities of Tannins(Pharmacological)
- 1-Deoxy (2,4-dinitrophenyl) osazones as Characterizing Derivative of 3-Ketoses
- Characterization of anti-herpes simplex virus type 1 activity of an alkaloid FK 3000 from Stephania cepharantha
- Effects of Ginseng in Nephrectomized Rats
- I-C-3 温脾湯改良方剤の腎摘ラットに及ぼす効果
- Human intestinal Bacteroides spp. RHEIN-I and RHEIN-II capable of transforming rhein to rheinanthrone, induce rhein-dependent diarrhea in rats
- P-2 丹参由来 Sodium tanshinone IIA sulfonate は Angiotensin II 誘導による培養心筋細胞肥大を軽減する
- L-097(30) 丹参製剤の適正使用のためのナレッジマネージメント : EBM の実践をめざして
- Metabolism of Paeoniflorin and Related Compounds by Human Intestinal Bacteria
- II-B-1 ヤナギ配糖体サリシンの再評価
- Enzymatic Sulfation of isoamyl Gallate and (-)-Epigallocatechin Gallate by Bacterial Arylsulfotransferase
- Inhibitory Effects of Glycyrrhetic Acid and Its Related Compounds on 3α-Hydroxysteroid Dehydrogenase of Rat Liver Cytosol
- Enzymatic Sulfation of Polyphenols Related to Tannins by Arylsulfotransferase
- Barbaloin Stimulates Growth of Eubacterium sp. Strain BAR, a Barbaloin-Metabolizing Bacterium from Human Feces
- Isolation of Novel Lignans, Heteroclitins F and G, from the Stems of Kadsura heteroclita, and Anti-lipid Peroxidative Actions of Heteroclitins A-G and Related Compounds in the in Vitro Rat Liver Homogenate System
- Structures of Alnusiin and Bicornin, New Hydrolyzable Tannins Having a Monolactonized Tergalloyl Group
- Studies on Inhibition Mechanism of Autoxidation by Tannins and Flavonoids. V. Radical-Scavenging Effects of Tannins and Related Polyphenols on 1,1-Diphenyl-2-picrylhydrazyl Radical
- Spectral and Chromatographic Analyses of Tannins. I. ^C Nuclear Magnetic Resonance Spectra of Hydrolyzable Tannins
- Ellagitannin Monomers and Oligomers from Euphorbia prostrata AIT. and Oligomers from Loropetalum chinense OLIV.
- EUPHORBIN E, A HYDROLYZABLE TANNIN DIMER OF HIGHLY OXIDIZED STRUCTURE, FROM EUPHORBIA HITRA
- Tannins and Related Polyphenols of Euphorbiaceous Plants. V. : Euphorbin C, an Equilibrated Dimeric Dehydroellagitannin Having a New Tetrameric Galloyl Group
- Equilibrium States of 3-Ketoses and Sedoheptulose-The Factor Favoring α-Furanose Formation of Coriose
- Coriose and Related Compounds. VII. Tautomerization of Crystalline α-Coriofuranose upon Trimethylsilylation
- Studies on Dental Caries Prevention by Traditional Medicines. VIII. : Inhibitory Effect of Various Tannins on Glucan Synthesis by Glucosyltransferase from Streptococcus mutans
- Tannins and Related Polyphenols of Theaceous Plants. VIII. Camelliatannins C and E, New Complex Tannins from Camellia japonica Leaves
- Tannins and Related Polyphenols of Melastomataceous Plants. VII. Nobotanins J and K, Trimeric and Tetrameric Hydrolyzable Tanins from Heterocentron roseum
- Tannins of Coriaria japonica A. GRAY. III. Structures of coriariins G, H, I and J
- Tannins and Related Polyphenols of Melastomataceous Plants. III. Nobotanins G, H and I, Dimeric Hydrolyzable Tannins from Heterocentron roseum
- Tannins and Related Polyphenols of Melastomataceous Plants. II. Nobotanins B, C and E, Hydrolyzable Tannin Dimer and Trimers from Tibouchina semidecandra COGN.
- Tannins and Related Polyphenols of Melastomataceous Plants. I. Hydrolyzable Tannins from Tibouchina semidecandra COGN.
- Tannins of Rosaceous Plants. IX. Rugosins D, E, F and G, Dimeric and Trimeric Hydrolyzable Tannins with Valoneoyl Group(s), from Flower Petals of Rosa rugosa THUNB.
- Gallotannins Having a 1,5-Anhydro-D-glucitol Core and Some Ellagitannins from Acer Species
- ^13C Nuclear Magnetic Resonance Spectra of Hydrolyzable Tannins. III. : Tannins Having ^1C_4 Glucose and C-Glucosidic Linkage
- Tannins and Related Polyphenols of Lythraceous Plants. III. Hydrolyzable Tannin Oligomers with Macrocyclic Structures, and Accompanying Tannins from Woodfordia fruticosa KURZ
- Tannins and Related Polyphenols of Theaceous Plants. IV. Monomeric and Dimeric Hydrolyzable Tannins Having a Dilactonized Valoneoyl Group from Schima wallichii KORTH.
- Woodfordin D and Oenothein A, Trimeric Hydrolyzable Tannins of Macro-Ring Structure with Anti-tumor Activity
- Tannins of Theaceous Plants. II. : Camelliins A and B, Two New Dimeric Hydrolyzable Tannins from Flower Buds of Camellia japonica L. and Camellia sasanqua THUNB.
- Phenolic Constituents of Licorice. III. Structures of Glicoricone and Licofuranone, and Inhibitory Effects of Licorice Constituents of Monoamine Oxidase
- Tannins of Rosaceus Medicinal Plants. V. : Hydrolyzable Tannins with Dehydrodigalloyl Group from Rosa laevigata MICHX.
- Constituents of Geranium thunbergii SIEB. et ZUCC. XIII. : Isolatilon of Water-Soluble Tannins by Centrifugal Partition Chromatography, and Biomimetic Synthesis of Elaeocarpusin
- DIMERIC ELLAGITANNINS IN PLANTS OF MELASTOMATACEAE
- Tannins and Related Polyphenols of Euphorbiaceous Plants. XI.Three New Hydrolyzable Tannins and a Polyphenol Glucoside from Euphorbia humifusa
- Tannins and Related Polyphenols of Rosaceous Medicinal Plants. IV. Roxbins A and B from Rosa roxburghii Fruits(Organic,Chemical)
- Corianin from Coriaria japonica A. GRAY, and Sesquiterpene Lactones from Loranthus parasiticus MERR. Used for Treatment of Schizophrenia(Organic,Chemical)
- Constituents of Geranium thunbergii SIEB. et ZUCC. IV. Ellagitannins. (2). Structure of Geraniin
- Studies on the Activities of Tannins and Related Compounds from Medicinal Plants and Drugs. VII. Effects of Extracts of Leaves of Artemisia Species, and Caffeic Acid and Chlorogenic Acid on Lipid Metabolic Injury in Rats Fed Peroxidized Oil
- Studies on the Activities of Tannins and Related Compounds from Medicinal Plants and Drugs. VI. Inhibitory Effects of Caffeoylquinic Acids on Histamine Release from Rat Peritoneal Mast Cells
- Studies on the Activities of Tannins and Related Compounds from Medicinal Plants and Drugs. IV. Effects of Various Extracts of Geranii herba and Geraniin on Liver Injury and Lipid Metabolism in Rats Fed Peroxidized Oil
- Studies on the Activities of Tannins and Related Compounds of Medicinal Plants and Drugs. III. Effects of Various Tannins and Related Compounds on Adrenocorticotropic Hormon-induced Lipolysis and Insulin-induced Lipogenesis from Glucose in Fat Cells. (2)
- Studies on the Activities of Tannins and Related Compounds of Medicinal Plants and Drugs. II. Effects of Various Tannins and Related Compounds on Adrenaline-induced Lipolysis in Fat Cells. (1)
- Studies on the Activities of Tannins and Related Compounds from Medicinal Plants and Drugs. I. Inhibitory Effects on Lipid Peroxidation in Mitochondria and Microsomes of Liver
- Antitumor Activities of Ellagitannins against Sarcoma-180 in Mice
- Tannins of Stachyurus Species. III. Stachyuranins A, B and C, Three New Complex Tannins from Stachyurus praecox Leaves
- Tannins of Euphorbiaceous Plants. XIII. New Hydrolyzable Tannins Having Phloroglucinol Residue from Glochidion rubrum BLUME
- CAMELLIATANNIN D, A NEW INHIBITOR OF BONE RESORPTION, FROM CAMELLIA JAPONICA
- New γ-Pyrone Glucoside, and Dimeric Ellagitannins from Gordonia axillaris
- Tannins of Theaceous Plants. V. Camelliatannins F, G and H, Three New Tannins from Camellia japonica L.
- Tannins of Tamaricaceous Plants. VI. Four New Trimeric Hydrolyzable Tannins from Reaumuria hirtella and Tamarix pakistanica
- Tannins of Tamaricaceous Plants. V. New Dimeric, Trimeric and Tetrameric Ellagitannins from Reaumuria hirtella
- Melitric Acids A and B, New Trimeric Caffeic Acid Derivatives from Melissa officinalis
- Carbonic Anhydrase Inhibitors from the Pericarps of Punica granatum L.
- Tannins of Tamaricaceous Plants. III. New Dimeric Hydrolyzable Tannins from Reaumuria hirtella
- Tannins and Related Polyphenols of Rosaceous Medicinal Plants. XII. Roshenins A-E, Dimeric Hydrolyzable Tannins from Rosa henryi BOUL.
- Tannins of Euphorbiaceous Plants. X. Antidesmin A, a New Dimeric Hydrolyzable Tannin from Antidesma pentandrum var. barbatum
- Circular Dichroism Studies on the Ellagitaimins-Nucleic Acids Interaction(Pharmacognosy,Chemical)
- Effects of Interaction of Tannins with Co-existing Substances. VII. : Inhibitory Effects of Tannins and Related Polyphenols on Xanthine Oxidase
- Phenolic Constituents of Licorice. II. : Structures of Licopyranocoumarin, Licoarylcoumarin and Glisoflavone, and Inhibitory Effects of Licorice Phenolics on Xanthine Oxidase
- Eucalbanins A, B and C, Monomeric and Dimeric Hydrolyzable Tannins from Eucalyptus alba REINW.
- Tannins and Related Polyphenols of Melastomataceous Plants. V. Three New Complex Tannins from Melastoma malabathricum L.
- Tannins of Tamaricaceous Plants. II. New Monomeirc and Dimeric Hydrolyzable Tannins from Reaumuria hirtella and Tamarix pakistanica
- Tannins of Stachyurus Species. II. Praecoxins A, B, C and D, Four New Hydrolyzable Tannins from Stachyurus praecox Leaves
- Tannins and Related Polyphenols of Euphorbiaceous Plants. VII. Tirucallins A, B and Euphorbin F, Monomeric and Dimeric Ellagitannins from Euphorbia tirucalli L.
- Tannins of Theaceous Plants. III. Camelliatannins A and B, Two New Complex Tannins from Camellia japonica L.
- Heterophylliins A, B, C, D and E, Ellagitannin Monomers and Dimers from Corylus heterophylla FISCH.
- GEMIN B AND C, DIMERIC ELLAGITANNINS FROM GEUM JAPONICUM
- ABSOLUTE CONFIGURATIONS OF CHEBULIC, CHEBULINIC AND CHEBULAGIC ACID
- Tannins of Rosaceous Medicinal Plants. I. Structures of Potentillin, Agrimonic Acids A and B, and Agrimoniin, a Dimeric Ellagitannin
- Tannins of Rosaceous Plants. VIII. Hydrolyzable Tannin Monomers Having a Valoneoyl Group from Flower Petals of Rosa rugosa THUNB.
- Tannins of Cornaceous Plants. I. Cornusiins A, B and C, Dimeric Monomeric and Trimeric Hydrolyzable Tannins from Cornus officinalis, and Orientation of Valoneoyl Group in Related Tannins
- CORNUSIIN A, A DIMERIC ELLAGITANNIN FORMING FOUR TAUTOMERS, AND ACCOMPANYING NEW TANNINS IN CORNUS OFFICINALIS
- RUGOSIN D, E, F AND G, DIMERIC AND TRIMERIC HYDROLYZABLE TANNINS
- RUGOSIN A, B, C AND PRAECOXIN A, TANNINS HAVING A VALONEOYL GROUP
- Coriose and Related Compounds. III. Synthesis of D-altro-3-Heptulose
- Structure of Catalpalactone, a New Phthalide from Catalpa Wood
- Color Reaction of Unsaturated Organic Compounds with Benzaldehyde and Sulfuric Acid.
- Coriamyrtin. IX. Methanolysis of Coriamyrtin.
- Coriamyrtin. VIII. Hydrogenation of Coriamyrtin.
- Studies on the Components of Coriaria japonica A. GRAY. XIV. Two New Compounds isolated from Old Stem and Seed.
- Relationship of the Structures of Tannins to the Binding Activities with Hemoglobin and Methylene Blue
- INHIBITORY EFFECT OF TANNINS ON DIRECT-ACTING MUTAGENS
- Trapanins A and B, : Oligomeric Hydrolyzable Tannins from Trapa japonica FLEROV.
- CASUARIIN, STACHYURIN AND STRICTININ, NEW ELLAGITANNINS FROM CASUARINA STRICTA AND STACHYURUS PRAECOX
- Effects of the Interaction of Tannins with Co-existing Substances. VI. : Effects of Tannins and Related Polyphenols on Superoxide Anion Radical, and on 1,1-Diphenyl-2-picrylhydrazyl Radical