Isolation of Novel Lignans, Heteroclitins F and G, from the Stems of Kadsura heteroclita, and Anti-lipid Peroxidative Actions of Heteroclitins A-G and Related Compounds in the in Vitro Rat Liver Homogenate System

概要

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From the stems of Kadsura heteroclita, two new lignans named heteroclitins F and G were isolated and their structures were determined by various spectroscopic means including an X-ray diffraction method. Dibenzocyclo-octadiene type lignans and related compounds isolated from the stems of K. heteroclita, potently inhibited the lipid peroxidation in the rat liver homogenate stimulated by Fe^<2+>-ascorbic acid, CCl_4-reduced form of nicotinamide adenine dinucleotide phosphate (NADPH) and adenosine 5'-diphosphate-NADPH.
社団法人日本薬学会の論文
1992-06-25