Phenolic Constituents of Licorice. II. : Structures of Licopyranocoumarin, Licoarylcoumarin and Glisoflavone, and Inhibitory Effects of Licorice Phenolics on Xanthine Oxidase
スポンサーリンク
概要
- 論文の詳細を見る
An anti-HIV (human immunodeficiency virus) phenolic constituent, licopyranocoumarin (4), and two other new phenolics named licoarylcoumarin (5) and glisoflavone (6) were isolated from Si-pei licorice (a commercial licorice; root and stolon of Glycyrrhiza sp. from the north-western region of China) using droplet countercurrent chromatography and centrifugal partition chromatography, and their structures were assigned based on chemical and spectroscopic data. Kaempferol 3-O-methyl ether (7) and licocoumarone (8) were also isolated from the licorice. The inhibitory effects of ten licorice phenolics on xanthine oxidase were examined. Licohalcone B (1), glycyrrhisoflavone (2), 8 and licochalcone A (19) showed 50% inhibition at the concentration of 1.3-5.6×10<-5>M.
- 公益社団法人日本薬学会の論文
- 1989-11-25
著者
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奥田 拓男
Faculty of Pharmaceutical Sciences, Okayama University
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波多野 力
Faculty of Pharmaceutical Sciences, Okayama University
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Hatano Tsutomu
エジプト
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野呂 忠敬
静岡県立大学
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奥村 智子
Faculty Of Pharmaceutical Sciences Okayama University
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Hatano Tsutomu
Department Of Pharmacognosy Okayama University Graduate School Of Medicine Dentistry And Pharmaceuti
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安原 多恵子
Faculty of Pharmaceutical Sciences, Okayama University
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奥田 拓男
Faculty Of Parmaceutical Sciences University
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福田 寿之
Faculty of Pharmaceutical Sciences, Okayama University
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野呂 忠敬
School of Pharmaceutical Sciences, University of Shizuoka
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野呂 忠敬
School Of Pharmaceutical Sciences University Of Shizuoka
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安原 多恵子
Faculty Of Pharmaceutical Sciences Okayama University
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