Studies on Differentiation Inducers. V. Steroid Glycosides from Periplocae Radicis Cortex
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概要
- 論文の詳細を見る
Six pregnane glycosides and three cardenolides were isolated as differentiation inducers using mouse myeloid leukemia (MI) cells from Periplocae Radicis Cortex (bark of Periploca sepium BGE., Asclepiadaceae). The cardenolides showed much higher activities than the pregnane glycosides. Besides these nine compounds, commercially available cardenolides were tested for their differentiation inducing activities using MI cells. Digitoxin and digoxin induced MI cells into phagocytic cells, but others did not. In the presence of 1 nM of actinomycin-D, the activity of steroid glycosides was enhanced against MI cells.
- 公益社団法人日本薬学会の論文
- 1995-09-15
著者
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黒柳 正典
静岡県大・薬
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上野 明
School Of Pharmaceutical Sciences University Of Shizuoka
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黒柳 正典
School of Bioresources, Hiroshima Prefectural University
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佐藤 裕子
School Of Pharmaceutical Sciences University Of Shizuoka
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Satoh Hiroko
School Of Pharmaceutical Sciences University Of Shizuoka
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宮瀬 敏男
School Of Pharmaceutical Sciences University Of Shizuoka
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梅原 薫
School of Pharmaceutical Sciences, University of Shizuoka
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上野 明
School Of Pharmaceutical Science University Of Shizuoka
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黒柳 正典
School Of Bioresources Hiroshima Prefectural University
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住井 直美
School of Pharmaceutical Sciences, University of Shizuoka
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Miyake T
School Of Pharmaceutical Sciences University Of Shizuoka
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Umehara K
School Of Pharmaceutical Sciences University Of Shizuoka
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梅原 薫
School Of Pharmaceutical Sciences University Of Shizuoka
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住井 直美
School Of Pharmaceutical Sciences University Of Shizuoka
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