Studies on Metabolites Produced by Aspergillus terreus var. aureus. I. Chemical Structures and Antimicrobial Activities of Metabolites Isolated from Culture Broth

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概要

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• A fungus which was identified as Aspergillus terreus var. aureus showed antifungal and antibacterial activities. Through the investigation of its metabolites, six compounds (1-6) were isolated ; emodin (1), dihydrogeodin (2), questin (3), sulochrin (5), the new metabolite 2-(3-chloro-4-methyl-γ-resorcyloyl)-5-hydroxy-m-anisic acid methyl ester (4), which is a monochloro derivative of sulochrin (5), and compound (6), the chemical structure of which has not yet been clarified. Dihydrogeodin (2), sulochrin (5), 4 and 6 showed antifungal and antibacterial activities, and 6 had especially strong antifungal activity towards Trichophyton mentagrophytes.

• 公益社団法人日本薬学会の論文
• 1983-12-25

著者

• 加藤 喜昭

  Osaka University Of Pharmaceutical Sciences

• 久保 真百合

  Osaka University of Pharmaceutical Sciences

• 竹本 常松

  徳島文理大学薬学部

• 野本 享資

  Suntory Institute for Bioorganic Research

• 竹本 常松

  Pharmaceutical Faculty Tokushima Bunri University

• 神木 照雄

  Wakayama Prefectural Institute of Public Health

• 神木 照雄

  Public Health Research Institute Of Kobe City

• 竹本 常松

  徳島文理大 薬

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