3 ブラジルニンジンおよび数種のPfaffia属植物の成分研究(ポスター発表の部)

概要

論文の詳細を見る
The crude drug 'Brazil ginseng' has been used medicinally in Brazil, chiefly as a tonic, an aphrodisiac and as antidiabetic.1 In the course of our investigation of the constituents of 'Brazil ginseng', we found that at least two kinds of plants, Pfaffia paniculata and P. iresinoides (Amaranthaceae) were used for the preparation of the crude drug. From the former plant, pfaffic acid(1), the hexacyclic nortriterpene and its glycosides possessing cytotoxicity were isolated. While from the latter, a large amount of ecdysterone(2) was isolated together with three new ecdysteroid glycosides and novel yellow pigments, iresinoside A(5) and B(7). These results stimulate our interests in investigating another kinds of plants of this family, P. glomerata, P. pulverulenta and P. tuberosa. All of the plants, except P. paniculata contained 2 as the major component. From P. glomerata and P. pulverulenta, rubrosterone(8)9 regarded as ecdysteroid metabolite was isolated. Four new pfaffane-type nortriterpenes(9-12) were isolated from P. pulverulenta together with 1 and β-D-glucuronopyranosyl pfaffate(13). The structures of the new compounds were elucidated by chemical and extensive spectral analyses. ^<13>C NMR data(Table 3) were fully assigned by using 2D NMR techniques(^1H-^1H COSY, ^<13>C-^1H COSY, long-range ^<13>C-^1H COSY and INADEQUATE).
天然有機化合物討論会の論文
1988-09-26