降圧性を目的とした芳香族オキシカルボン酸誘導体の合成(1)(II 予防および治療)(A 基礎的研究)

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概要

• 論文の詳細を見る

• Aromatic hydroxycarboxylic acid derivative was designed expecting hypotensive property on the basis of structural analogy with known hypotensive isoflavonoides. In order to develop a convenient synthetic route of the designed type of compounds, a general synthetic method of acylated salicylic acids was established. The synthesized 8 acylsalicylic acids, 5a-5h, were provided for pharmacological screening tests and showed no significant hypotensive activity but some inhibitory effect on heat-denaturation of bovine serum albumin.

• 近畿大学の論文
• 1982-12-31

著者

• 竹村 庄司

  Faculty Of Pharmaceutical Sciences Kinki University

• 竹村 庄司

  近畿大学薬学部医薬品化学教室

• 三木 康義

  近畿大学薬学部医薬品化学教室

• 吾妻 由子

  近畿大学薬学部

• 正垣 千幸

  近畿大学薬学部医薬品化学教室

• 吾妻 由子

  Faculty Of Pharmaceutical Sciences Kinki University

• 三木 康義

  近畿大学 薬学部

• 竹村 庄司

  Faculty of Pharmaceutical Sciences, Kinki University

• 三木 康義

  近畿大学薬学部

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