Stereoselective Reduction of α- and β-Keto Esters with Aerobic Thermophiles, Bacillus Strains

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概要

• 論文の詳細を見る

• The first example of stereoselective reduction with aerobic thermophiles is reported. Various α- and β-keto esters were reduced stereoselectively to the corresponding alcohols by the aerobic thermophiles, Bacillus strains. In particular, the reduction of ethyl 3-methyl-2-oxobutanoate with B. stearothermophilus DSM 297 gave the corresponding (R)-alcohol with high yield in excellent enantioselectively (>99% e.e.). The conversions of keto esters to the corresponding hydroxy esters with Bacillus strains were increased by introduction of glycerol in the reaction mixture as an additive.

• 社団法人日本農芸化学会の論文
• 1996-11-23

著者

• 中村 薫

  京都大学化学研究所

• 中島 伸佳

  Graduate School Of Health And Welfare Okayama Prefectural University

• 中島 伸佳

  岡山県立大学短期大学部

• 中島 伸佳

  岡山県立短大

• NAKAJIMA Nobuyoshi

  Department of Nutritional Science, Okayama Prefectural University

• ISHIHARA Kohji

  Department of Chemistry, Kyoto University of Education

• NAKAMURA Kaoru

  Institute for Chemical Research, Kyoto University

• YAMAGUCHI HITOMI

  Department of Chemistry, Kyoto University of Eduction

• OHSHIMA TOSHIHISA

  Department of Chemistry, Kyoto University of Education

• IWAI Keisuke

  Department of Chemistry, Kyoto University of Education

• 中村 薫

  京大 化研

• Iwai K

  Kobe Women's Univ. Hyogo Jpn

• Ishihara K

  Dep. Of Life Sci. Okayama Univ. Of Sci. 1-1 Ridai-cho Kita-ku Okayama 700-0005 Jpn

• Nakajima Nobuyoshi

  Graduate School Of Health And Welfare Okayama Prefectural University

• Nakajima Nobuyoshi

  Department Of Nutritional Science Faculty Of Health And Welfare Okayama Prefectural University

• Nagahama Kazuhiro

  Department Of Applied Microbial Technology The Kumanoto Institute Of Technology

• Nakamura Kaoru

  Institute For Chemical Research Kyoto University

• Iwai K

  Shizuoka Univ. Shizuoka Jpn

• Yamaguchi Hitomi

  Department Of Chemical Science And Engineering Kobe University

• Nakamura Kahoru

  Department Of Nutrition Tokyo University Of Agriculture

• Yamaguchi H

  Research And Development Center Nagase & Co. Ltd.

• Ohshima T

  Microbial Genetics Division Institute Of Genetic Resources Faculty Of Agriculture Kyushu University

• Ohshima Toshihisa

  Department Of Biological Science And Technology Faculty Of Engineering The University Of Tokushima

• Ohshima Toshihisa

  Microbial Genetics Division, Institute of Genetic Resources, Faculty of Agriculture, Kyushu University

• Nakajima Nobuyoshi

  Department of Food and Nutrition, Okayama Prefectural Junior College

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