P-12 植物培養細胞による活性フェノール化合物の配糖化(ポスター発表の部)
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概要
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Flavonoids are phenolic compounds widely present in plants and foods of plant origin. (+)-Catechin, (-)-epicatechin, Querucetin,, and taxifolin are type of flavons, daidzein and genistein are type of isoflavons and then resveratrol is type of stilbene. Taxiforin is included in Larix sibirica. Chrysin and querucetin are included in peel of citrous. Daidzein and genistein exist in soy beens. Resveratrol is included in red wine. These compounds are known to have the biological activities including an antioxidant property, anti-inflammatory and carcinogenic depression effects. These compounds are used as agents and food ingredients. Irrespective of such biological activities, the use of these compounds has been limited, because of their low solubility. Higher plants accumulate a wide range of glycosides as secondary metabolites, and are capable of conjugating sugar residues not only to endogenous metabolic intermediates but also to xenobiotics. To enhance the water-solubility of their flavonoids, we investigated the glycosylation using Eucalyptus perriniana. Eucalyptus perriniana plant cultured cells were tested for the glycosylation toward there compounds. As a result, (-)-epicatechin, daidzein and genistein were glycosylated at C7-position of hydroxyl group in the substrate molecules. (+)-Catechin was glycosylated at C7, C3'-position of hydroxyl group. Querucetin was glycosylated at C3-position of hydroxyl group. Taxifolin was glycosylated at C7 and C4'-position of hydroxyl group. Also, resveratrol was glycosylated at C3-position of hydroxyl group.
- 天然有機化合物討論会の論文
- 2008-09-01
著者
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石原 浩二
岡山理科大学理学部臨床生命科学科
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浜田 博喜
岡山理大理
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小林 達成
岡山理大院
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大広 あずさ
岡山理大院
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石原 浩二
岡山理大理
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下田 恵
大分大医
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中島 伸佳
岡山県立大
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小林 達成
岡山理科大学大学院理学研究科総合理学専攻
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中島 伸佳
Graduate School Of Health And Welfare Okayama Prefectural University
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中島 伸佳
岡山県立大学短期大学部
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Nakajima Nobuyoshi
Graduate School Of Health And Welfare Okayama Prefectural University
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中島 伸佳
Department Of Nutritional Science Faculty Of Health And Welfare Science Okayama Prefectural Universi
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