Synthesis and Activity of Pyrimidinylpropenamide Antibiotics : The Alkyl Analogues of Sparsomycin(Organic Chemistry)

スポンサーリンク

概要

• 論文の詳細を見る

• Facile syntheses of sparsomycin (3) and its four analogues (4-7) based on diastereoselective oxidation of sulfide, sulfenylation, and coupling of 6-methyluracylacryllic acid with monooxodithioacetal amine, are described. Studies on the biological activity of morphological reversion on src^<ts>-NRK cells were also carried out.

• 社団法人日本農芸化学会の論文
• 2003-12-23

著者

• 中島 伸佳

  Graduate School Of Health And Welfare Okayama Prefectural University

• MATSUURA Nobuyasu

  Biotechnology Research Center,Toyama Prefectural University

• Matsuura N

  Biotechnology Research Center Toyama Prefectural University

• Matsuura N

  Department Of Life Science Okayama University Of Science

• Matsuura Nobuyasu

  富山県立大学生物工学研究センター

• UBUKATA Makoto

  Biotechnology Research Center, Toyama Prefectural University

• Nakajima Noriyuki

  Biotechno-logy Research Center, Toyama Prefectural University

• ENOMOTO Takeshi

  Biotechnology Research Center, Toyama Prefectural University

• WATANABE Takehiro

  Biotechnology Research Center, Toyama Prefectural University

• Enomoto Takeshi

  Biotechnology Research Center Toyama Prefectural University

• Matsuura Nobuyasu

  Biotechnology Research Center Toyama Prefectural University

• Matsuura Nobuyasu

  Department Of Life Science Okayama University Of Science

• Nakajima Noriyuki

  Biotechnology Research Center Toyama Prefectural University

• Nakajima Noriyuki

  Biotechno-logy Research Center Toyama Prefectural University

• Ubukata M

  Hokkaido Univ. Sapporo Jpn

• Ubukata Makoto

  Biotechnology Research Center Toyama Prefecture University

• Nakajima N

  Biotechnology Research Center Toyama Prefectural University

• Ubukata Makoto

  Biotechnology Research Center Toyama Prefectural University

• Watanabe Takehiro

  Biotechnology Research Center Toyama Prefectural University

関連論文

• イソクエルシトリンによるアコヤガイ赤変病の軽減
• 植物性素材を原料とした「乳酸菌・酵母発酵エキス(PELY)」に関する研究
• エコシステムを利用した瀬戸内海沿岸の海洋環境汚染物質の除去・回収法の開発--環境ホルモン関連物質を中心として
• 瀬戸内海総合開発特別研究(第36回伊原木記念賞)エコシステムを利用した瀬戸内海沿岸の海洋汚染物質の除去・回収法の開発
• 海洋性微細藻類を用いる内分泌攪乱物質(環境ホルモン)の機能改変と海洋汚染物質の除去に関する研究
• 食品添加物としての、天然植物色素の酵素的安定化と、抗酸化性を中心としたそれらの付随的生理機能の解明
• P-12 植物培養細胞による活性フェノール化合物の配糖化(ポスター発表の部)
• Further Characterization of Earthworm Serine Proteases : Cleavage Specificity Against Peptide Substrates and on Autolysis
• Multi-enzymatic Glucosylation Using Eucalyptus UDP-Glucosyltransferase Coupled UDPglucose-Fermentation by Bakers'Yeast
• Lipase-catalyzed Synthesis of Arbutin Cinnamate in an Organic Solvent and Application of Transesterification to Stabilize Plant Pigments
• Preparation of Optically Active α-Hydroxy Esters : Stereoselective Reduction of α-Keto Esters Using Thermophilic Actinomycetes
• Amino Acid Sequence and Characterization of Aldo-keto Reductase from Bakers' Yeast
• Stereoselective Reduction of α- and β-Keto Esters with Aerobic Thermophiles, Bacillus Strains
• Protein Sequences of Two Keto Ester Reductases: Possible Identity as Hypothetical Proteins
• Enzymatic Production of (S)-1-Acetoxy-2-Alkanol with Bakers' Yeast Cell-Free Extract in a Membrane Reactor
• Tannins and Related Polyphenols,HIV Reverse Transcriptase Inhibitors, from Rosa woodsii
• A Novel Zinc-containing α-Keto Ester Reductase from Actinomycete : An Approach Based on Protein Chemistry and Bioinformatics
• New Types of Liposidomycins that Inhibit Bacterial Peptidoglycan Synthesis and are Produced by Streptomyces II. Isolation and Structure Elucidaion
• Acetophthalidin, a Novel Inhibitor of Mammalian Cell Cycle, Produced by a Fungus Isolated from a Sea Sediment
• Structure-Activity Relationship within a Series of Degradation Products of Tautomycin
• Tryprostatins A and B, Novel Mammalian Cell Cycle Inhibitors Produced by Aspergillus fumigatus
• P-337 Synthesis and Activity of Acyl-substituted Catechin, Epicatechin and Procyanidin dimers
• Degradation of Pectic Substances by Two Pectate Lyases from a Human Intestinal Bacterium, Clostridium butyricum-beijerinckii Group
• Enzymatic preparation of arbutin derivatives : Lipase-catalyzed direct acylation without the need of vinyl ester as an acyl donor(MICROBIAL PHYSIOLOGY AND BIOTECHNOLOGY)
• Synthesis of Unnatural Mono- and Oligosaccharides of Farnesol, Geraniol, and (S)-Perillyl Alcohol by Biocatalytic Glycosylations
• Enhancement of Water-Solubility and Bioactivity of Paclitaxel Using Modified Cyclodextrins(METHODS)
• 有機溶媒に耐性で常温においては自己消化による失活を伴わない「ミミズプロテアーゼ」の物質合成・変換への応用 (特集 物質合成の設計図にブレークスルーを--酵素触媒の活躍と未来)
• Analysis of Isoflavone Content in Tempeh, a Fermented Soybean, and Preparation of a New Isoflavone-Enriched Tempeh(BREWING AND FOOD TECHNOLOGY)
• An Isozyme of Earthworm Serine Proteases Acts on Hydrolysis of Triacylglycerol
• Biotransformation of (+)-catechin by plant cultured cells of Eucalyptus perriniana
• Purification and Characterization of α-Keto Amide Reductase from Saccharomyces cerevisiae
• Stereoselective biotransformation of limonene and limonene oxide by cyanobacterium, Synechococcus sp. PCC 7942
• Damage to Cultivated Japanese Pearl Oysters by Oxidative Stress That Was Related to "Mass Mortality"(Biochemistry & Molecular Biology)
• One- step Glucosylation of Capsaicinoids by Cultured Cells of Phytolacca americana
• Comparison of Acylated Plant Pigments : Light-resistance and Radical-scavenging Ability(Biochemistry & Molecular Biology)
• Further Stabilization of Earthworm Serine Protease by Chemical Modification and Immobilization(Biochemistry & Molecular Biology)
• Enzyme-catalyzed Acylation of Plant Polyphenols for Interpretation of Their Functions
• Stereoselective Reduction of Ketone and Enone using Plant Cell Cultures
• Purification and Characterization of Two α-Keto Ester Reductases from Streptomyces thermocyaneoviolaceus IFO 14271(Microbiology & Fermentation Technology)
• Functional Glucosylation of Kojic Acid and Daidzein with the Eucalyptus Membrane-Associated UDP-Glucosyltransferase Reaction System
• Stereocontrolled Reduction of α-and β-Keto Esters with Micro Green Algae, Chlorella Strains
• Regioselective Acylation of Flavonoid Glucoside with Aromatic Acid by an Enzymatic Reaction System from Cultured Cells of Ipomoea batatas
• カツオ(Katsuwonus pelamis)塩辛由来の新規な線溶プロテア-ゼ--精製と性質
• ミミズ(Lumbricus rubellus)細胞中に発見されたきわめて安定な線溶酵素-3-蛋白化学的性質と分子構造
• ミミズ(Lumbricus rubellus)細胞中に発見されたきわめて安定な線溶酵素-2-単離・精製と酵素科学的性質
• A Pharmacophore Model of Tautomycin, an Inhibitor of Protein Phosphatases I and 2A
• Confirmation of the Relative Stereochemistry at C-23 and C-24 of Tautomycin
• Indocarbazostatins C and D, New Inhibitors of NGF-induced Neuronal Differentiation in PC12 Cells
• Synthesis and Activity of Pyrimidinylpropenamide Antibiotics : The Alkyl Analogues of Sparsomycin(Organic Chemistry)
• Indocarbazostatin and Indocarbazostatin B, Novel Inhibitors of NGF-induced Neuronal Differentiation in PC12 Cells : II. Isolation, Physicochemical Properties and Structural Elucidation
• Indocarbazostatin and Indocarbazostatin B, Novel Inhibitors of NGF-induced Neuronal Differentiation in PC12 Cells : I. Screening, Taxonomy, Fermentation and Biological Activities
• Indocardazostatin, a Novel Inhibitor of NGF-induced Neurite Outgrowth from Rat Pheochromocytoma PC12 Cells
• Stilbenoids in Lianas of Gnetum parvifolium
• Stilbenoids in Lianas of Gnetum parvifolium
• New Hydrolyzable Tannins, Shephagenins A and B, from Shepherdia argentea as HIV-1 Reverse Transcriptase Inhibitors
• Sparoxomycins A1 and A2, New Inducers of the Flat Reversion of NRK Cells Transformed by Temperature Sensitive Rous Sarcoma Virus I. Taxonomy of the Producing Organism, Fermentation and Biological Activity
• Cloning of the Gene Cluster Responsible for the Biosynthesis of Brasilicardin A, a Unique Diterpenoid
• Presence of Copalyl Diphosphate Synthase Gene in an Actinomycete Possessing the Mevalonate Pathway
• Stable Earthworm Serine Proteases : Application of the Protease Function and Usefulness of the Earthworm Autolysate
• Synthetic Studies of Proanthocyanidins. Highly Stereoselective Synthesis of the Catechin Dimer, Procyanidin-B3(Organic Chemistry)
• Synthetic Studies of an 18-Membered Antitumor Macrolide, Tedanolide. 6. Synthesis of a Key Intermediate via a Highly Efficient Macrolactonization of Computer-Aid Designed Seco-Acid
• synthetic Studies of an 18-Membered Antitumor Macrolide, Tedanolide.5. Stereoselective Synthesis of the C13-C23 Part via Condensation of Two Fragments, C13-C17 and C18-C21,by Taking Adventage of the 3,4-Dimethoxybenzyl Protecting Group
• Synthetic Studies of the 18-Membered Antitumor Macrolide, Tedanolide. 3. Stereocontrolled Synthesis of the C1-C12 Part via a Synthesis of the C1-C7 Fragment by a Mismatched but Efficient Sharpless Dihydroxylation and Its Coupling with the C8-C11 Fragment
• Synthetic Studies of 18-Membered Antitumor Macrolide, Tedanolide. 2. Stereoselective Synthesis of the C1-C7 Fragment via a Mismatched but Highly Efficient Sharpless Dihydroxylation
• Screening System for the Maillard Reaction Inhibitor from Natural Product Extracts
• A Sensitive Radial Diffusion Method for the Determination of Several Proteases
• 機能性食品としての海洋生物--無脊椎動物および藻類中に見出された血栓溶解関連物質
• Purification and Characterization of a Tuliposide-Converting Enzyme from Bulbs of Tulipa gesneriana
• Edge-Layer Theory for Shallow-Water Waves over a Step-Reflection and Transmission of a Soliton
• Facile Synthesis of Cyanogen Glycosides (R)-Prunasin, Linamarin and (S)-Heterodendrin
• Biotransformation of Cinnamic Acid, p-Coumaric Acid, Caffeic Acid, and Ferulic Acid by Plant Cell Cultures of Eucalyptus perriniana
• Stereoselective Reduction of Carbonyl Compounds with Actinomycete : Purification and Characterization of Three α-Keto Ester Reductases from Streptomyces avermitilis
• 血栓溶解酵素ナットウキナ-ゼの活性測定法
• P-356 The Mechanism Underlying Blue Color Development in Tulips
• Perianth Bottom-Specific Blue Color Development in Tulip cv. Murasakizuisho Requires Ferric Ions
• Enzymatic Production of β-Thujaplicin 2-O-β-D-Glucoside in a Membrane Reactor Using an Insoluble UDP-Glucosyltransferase Fraction from Cultured Cells of Eucalyptus perriniana
• Lipase-Catalyzed Direct and Regioselective Acylation of Flavonoid Glucoside for Mechanistic Investigation of Stable Plant Pigments
• Tannins and Related Polyphenols, HIV Reverse Transcriptase Inhibitors, from Rosa woodsii(Natural Medicine Note)
• 34 THIAMAZOL OR PROPILTHIOURACIL AND L-T4 COMBINATION THERAPY FOR INFANTS BORN TO MOTHER WITH GRAVES' DISEASE
• 46 GENETIC ANALYSIS IN PATIENTS WITH CONGENITAL NEPHROGENIC DIABETES INSIPIDUS
• 48 DIAGNOSIS OF MILD CONGENIAL HYPOTHYROIDISM ETIOLOGY OF THE DISEASE AND CONFIRMATORY TEST PERFORMED BY COUNCIL MEMBERS OF THE JSPE FOR DIAGNOSIS OF THE DISEASE
• 54 TWO PUBERTAL BOYS WITH IMPAIRED GLUCOSE TOLERANCE AND THRIFTY PHENOTYPE
• 50 ASSOCIATION STUDY OF HUMAN MUT T HOMOLOGUE 1 GENE VAL83MET POLYMORPHISM WITH TYPE 1 DIABETES MELLrrus.
• 179 α-TUBULIN GENE EXPRESSION IN THE BRAIN OF rdw RATS WITH CONGENITAL HYPOTHYROIDISM
• 海洋生物と血栓溶解関連物質

もっと見る 閉じる

スポンサーリンク