synthetic Studies of an 18-Membered Antitumor Macrolide, Tedanolide.5. Stereoselective Synthesis of the C13-C23 Part via Condensation of Two Fragments, C13-C17 and C18-C21,by Taking Adventage of the 3,4-Dimethoxybenzyl Protecting Group
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概要
- 論文の詳細を見る
An efficient and stereoselective synthesis of the C13-C23 part (8) was achieved starting from methyl (R)-and (S)-3-hydroxy-2-methylpropionates (9) via coupling of the C13-C17 aldehyde (6), prepared by Evens asymmetric aldol reaction, with the C18-C21 iodoalkene (5b) by taking advantage of the 3,4-dimethoxybenzyl protecting group.
- 公益社団法人日本薬学会の論文
- 1999-09-15
著者
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Mori Masao
Faculty Of Hospital Pharmacy Saga Medical School
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Maeda Hiroshi
Department of Urology, Shinko Clinic
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Yonemitsu O
Hokkaido Univ. Sapporo Jpn
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Mori M
Department Of Pharmacy Saga University Hospital
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Mori M
Faculty Of Hospital Pharmacy Saga Medical School
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Mori M
The Institute Of Physical And Chemical Research (riken)
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Nakajima Noriyuki
Biotechno-logy Research Center, Toyama Prefectural University
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YONEMITSU Osamu
Department of Chemistry, Okayama University of Science
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Nakajima Noriyuki
Biotechnology Center Toyama Prefectural University
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Nakajima Noriyuki
Biotechno-logy Research Center Toyama Prefectural University
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Zheng B‐z
Okayama Univ. Sci. Okayama Jpn
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Zheng Bao-zhong
Department Of Chemistry Okayama University Of Science
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森 昌斗
Hospital Pharmacy Saga Medical School
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Mori Michiko
Department Of Pathology Sapporo Medical University School Of Medicine
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Matsushima Tomohiro
Faculty Of Pharmaceutical Sciences Hokkaido University
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KUSAKA Shin-ichi
Deparment of Chemistry, Okayama University of Science
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UENISHI Jun-ichi
Kyoto Pharmaceutical University
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Yonemitsu Osamu
Departmen Of Chemistry Okayama University Of Science
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Kusaka Shin-ichi
Deparment Of Chemistry Okayama University Of Science
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Nakajima N
Biotechno-logy Research Center Toyama Prefectural University
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Uenishi J
Department Of Chemistry Okayama University Of Science
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Maeda Hiroshi
Department Of Urology Kurashiki Central Hospital
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Maeda Hiroshi
Department Of Experimental Pathology Cancer Institute
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Maeda Hiroshi
Department Of Applied Molecular Biology And Biochemistry Tokyo University Of Agriculture And Technol
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Maeda Hiroshi
Department Of Advanced Materials Science And Engineering Graduate School Of Engineering Yamaguchi Un
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MORI Michiko
Department of Agricultural Chemistry, Faculty of Agriculture, Utsunomiya University
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