Antiproliferative Constituents in Umbelliferae Plants II. : Screening for Polyacetylenes in Some Umbelliferae Plants, and Isolation of Panaxynol and Falcarindiol from the Root of Heracleum moellendorffii
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概要
- 論文の詳細を見る
Methanol extracts of 36 samples of 21 Umbelliferae plants were screened for polyacetylenic compounds using the ELISA for panaxytriol, and their antiproliferative activity was checked by MTT assay using the tumor cell lines MK-1,HeLa and B16F10. The presence of antiproliferative polyacetylenes was suggested in Angelica acutiloba (fruit), Anethum graveolens (root), Bupleurum rotundifolium (fruit), Carum carvi (fruit and root), Coriandrum sativum (fruit), Cryptotaenia japonica (leaf), Glehnia littoralis (fruit), Heracleum moellendorffii (root) and Torilis japonica (fruit).Panaxynol and falcarindiol were successfully isolated from the root of Heracleum moellendorffii as antiproliferative polyacetylenes.
- 社団法人日本薬学会の論文
- 1998-03-15
著者
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岡部 光
Faculty Of Pharmaceutical Sciences Fukuoka University
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Katano Mitsuo
Department Of Surgery Saga Medical School
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Katano Mitsuo
Department Of Cancer Therapy And Research Graduate School Of Medical Sciences Kyushu University
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Mori Masao
Faculty Of Hospital Pharmacy Saga Medical School
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OKABE Hikaru
Faculty of Pharmaceutical Sciences, Fukuoka University
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Okabe Hikaru
Faculty Of Pharmaceutical Sciences Fukuoka University
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岡部 光
福岡大学
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Okabe Hikaru
福岡大学 薬学部
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岡部 光
福岡大学薬学部
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Katano M
Department Of Surgery Saga Medical School
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Mori M
Department Of Pharmacy Saga University Hospital
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Mori M
Faculty Of Hospital Pharmacy Saga Medical School
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Mori M
The Institute Of Physical And Chemical Research (riken)
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NAKANO Yukitaka
Faculty of Hospital Pharmacy, Saga Medical School
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MATSUNAGA Hisashi
Faculty of Hospital Pharmacy, Saga Medical School
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MORI Masato
Faculty of Hospital Pharmacy, Saga Medical School
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SAITA Tetsuya
Faculty of Hospital Pharmacy
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Saita T
Department Of Pharmacy Saga University Hospital
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森 昌斗
Hospital Pharmacy Saga Medical School
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Matsunaga H
Takeda Chemical Ind. Ltd. Osaka Jpn
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Nakano Yukitaka
Faculty Of Hospital Pharmacy Saga Medical School
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Matsunaga H
Dep. Of Pharmacy Okayama Univ. Hospital
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