Trypanocidal Constituents in Plants 4. Withanolides from the Aerial Parts of Physalis angulata(Pharmacognosy)

スポンサーリンク

概要

• 論文の詳細を見る

• The constituents of the aerial parts of Physalis angulata (Solanaceae) were investigated based on the plant's trypanocidal activity against epimastigotes of Trypanosoma cruzi, the etiologic agent for Chagas' disease. Four new withanolides were isolated, along with six known ones, from the active fraction. Their structures were determined by spectroscopic analysis. Trypanocidal activity against trypomastigotes, an infectious form of T. cruzi, was also estimated, as well as cytotoxic activity against human uterine carcinoma (HeLa) cells in vitro. Evaluation of trypanocidal activity using the colorimetric reagent Cell Counting Kit-8 was also examined.

• 公益社団法人日本薬学会の論文
• 2004-02-01

著者

• 岡部 光

  Faculty Of Pharmaceutical Sciences Fukuoka University

• 阿部 フミ子

  Faculty Of Pharmaceutical Sciences Fukuoka University

• 赤羽 啓栄

  福岡医大

• 赤羽 啓栄

  School Of Medicine Fukuoka University

• 赤羽 啓栄

  九州大学 寄生虫

• 赤羽 啓栄

  信州大・志賀高原生研

• 赤羽 啓栄

  福岡大学 病理学

• ABE Fumiko

  Faculty of Pharmaceutical Sciences, Fukuoka University

• NAGAFUJI Shinya

  Faculty of Pharmaceutical Sciences, Fukuoka University

• OKABE Hikaru

  Faculty of Pharmaceutical Sciences, Fukuoka University

• Okabe Hikaru

  Faculty Of Pharmaceutical Sciences Fukuoka University

• 岡部 光

  福岡大学

• Okabe Hikaru

  福岡大学 薬学部

• 岡部 光

  福岡大学薬学部

• Akahane H

  School Of Medicine Fukuoka University

• 赤羽 啓栄

  福岡大医

• Abe Fumiko

  Faculty Of Pharmaceutical Science Fukuoka University

• AKAHANE Hiroshige

  Fukuoka University School of Medicine

• Nagafuji Shinya

  Faculty Of Pharmaceutical Sciences Fukuoka University

• Akahane Hiroshige

  福岡大学医学部寄生虫学

• 赤羽 啓栄

  福岡大学 医学部 寄生虫学 教室

関連論文

• D222 ハルザキヤマガラシサポニンおよび類縁サポニンのコナガ摂食阻害活性(寄主選択・耐虫性)
• A304 ハルザキヤマガラシに含まれるコナガ幼虫摂食阻害物質の単離(生理活性物質)
• Trypanocidal Constituents in Plants 6. Minor Withanolides from the Aerial Parts of Physalis angulata
• ウスバサイシンAsiasarum sieboldii F. Maekawaの発芽特性
• Trypanocidal Constituents in Plants 5. Evaluation of Some Mexican Plants for Their Trypanocidal Activity and Active Constituents in the Seeds of Persea americana(Pharmacognosy)
• Examination for Estrogenic Activities of Soyasaponin I and Related Compounds
• Soy Isoflavone Metabolites Isolated from Human Urine
• Hepatoprotective Constituents in Plants 14. Effects of Soyasapogenol B, Sophoradiol, and Their Glucuronides on the Cytotoxicity of tert-Butyl Hydroperoxide to HepG2 Cells(Pharmacognosy)
• Gas-Liquid Chromatographic Separation of Aldose Enantiomers as Trimethylsilyl Ethers of Methyl 2-(Polyhydroxyalkyl)-thiazolidine-4(R)-carboxylates(Organic,Chemical)
• Antiproliferative Activity of the Main Constituents from Phyllanthus emblica
• Antiproliferative Activity of Phenylpropanoid Ester Glycosides from Ligustrum purpurascens
• Studies on the Constituents of Momordica cochinchinensis SPRENG. I. Isolation and Characterization of the Seed Saponins, Momordica Sapponins I and II
• Antiproliferative Constituents from Umbelliferae Plants. V. A New Furanocoumarin and Falcarindiol Furanocoumarin Ethers from the Root of Angelica japonica
• Antiproliferative Constituents in Umbelliferae Plants. IV. Constituents in the Fruits of Anthriscus sylvestris HOFFM.
• Antiproliferative Constituents in Umbelliferae Plants. III. Constituents in the Root and the Ground Part of Anthriscus sylvestris HOFFM.
• Antiproliferative Constituents in Umbelliferae Plants II. : Screening for Polyacetylenes in Some Umbelliferae Plants, and Isolation of Panaxynol and Falcarindiol from the Root of Heracleum moellendorffii
• Structures and Antiproliferative Activity of Saponins from Sechium pittieri and S. talamancense
• スンバワ島産Alstonia villosa葉から単離したインドールアルカロイド(Alstonia第6報)(発表論文抄録(2000))
• Three New Withanolides, Physagulins E, F and G from Physalis angulate L.
• Three New Withanolides, Physagulins A, B and D from Physalis angulata L.
• Studies on the Constituents of Actinostemma lobatum MAXIM. VI. Structures of Lobatosides I, J and K, Oleanolic Acid and Gypsogenin Glycosides Isolated from the Seed
• Studies on the Constituents of Actinostemma lobatum MAXIM. V. : Structures of Lobatosides B, E, F and G, the Dicrotalic Acid Esters of Bayogenin Bisdesmosides Isolated from the Herb
• Studies on the Constituents of Actinostemma lobatum MAXIM. IV. Structures of Lobatosides C, D and H, the Dicrotalic Acid Esters of Bayogenin Bisdesmosides Isolated from the Herb
• Studies on the Constituents of Actinostemma lobatum MAXIM. III. : Structures of Actinostemmosides E and F, New Baccharane-Type Triterpene Glycosides Isolated from the Herb
• Studies on the Constituents of Actinostemma lobatum MAXIM. I. Structures of Actinostemmosides A, B, C and D, Dammarane Triterpene Glycosides Isolated from the Herb(Organic,Chemical)
• Minor Cardenolide Glycosides and a Cardenolide from the Leaves of Anodendron affine (Anodendron. VIII)
• Studies on the Constituents of Thladiantha dubia BUNGE. I. : The Structures of Dubiosides A, B and C, the Quillaic Acid Glucuronide Saponins Isolated from the Tuber
• SEPARATION OF ALDOSE ENANTIOMERS BY GAS-LIQUID CHROMATOGRAPHY
• Neridienone A, a C_-Steroid in Nerium odorum
• Inhibitors of Angiotensin-Converting Enzyme in Crude Drugs. II
• Inhibitors of Angiotensin Converting Enzyme in Crude Drugs. I
• Studies on the Constituents of Aster scaber THUNB, IV. Structures of Four New Echinocystic Acid Glycosides Isolated from the Herb
• Studies on the Constitutents of Aster scaber THUNB. II. Structures of Echinocystic Acid Glycosides Isolated from the Root
• Studies on teh Constitutents of Aster scaber THUNB.I. Structures of Scaberosides, Oleanolic Acid Glycosides Isolated from the Root
• Studies on the Constituents of Luffa acutangula ROXB. II. Structures of Acutosides H and I, Oleanolic Acid Saponins Isolated from the Seed
• Studies on the Constituents of Luffa acutangula ROXB. I. Structures of Acutosides A-G, Oleanane-Type Triterpene Saponins Isolated from the Herb
• Studies on the Constituents of Aster tataricus L. f. IV. : Structures of Aster Saponins Isolated from the Herb
• Studies on the Constituents of Thladiantha dubia BUNGE. II. : Structures of Dubiosides D, E and F, Neutral Saponins of Quillaic Acid Isolated from the Tuber
• Studies on Resin Glycosides. III. Complete Structures of Pharbitic Acids C and D
• Studies on Resin Glycosides. II. Unhomogeneity of "Pharbitic Acid" and Isolation and Partial Structures of Pharbitic Acids C and D, the Major Constituents of "Pharbitic Acid"
• Studies on Resin Glycosides. I. Reinvestigation of the Components of Pharbitin, a Resin Glycoside of the Seeds of Pharbitis Nil CHOISY
• Studies on Rhubarb (Rhei Rhizoma). II. Anthraquinone Glycosides
• Inhibitory Effects of Cucurbitane Triterpenoids on Epstein-Barr Virus Activation and Two-Stage Carcinogenesis of Skin Tumor. II
• Studies on the Constituents of the Root of Cayaponia tayuya (VELL.) COGN. III. Structures of Cayaponosides, 29-Nor-1,2,3,4,5,10-hexadehydrocucurbit-6-ene Glucosides
• Studies on the Constituents of the Root of Cayaponia tayuya (VELL.) COGN. II. Structures of Cayaponosides, New 29-Nor-2,11-dioxocucurbita-3,5-diene Glucosides
• Studies on the Constituents of the Root of Cayaponia tayuya (VELL.) COGN. I. Structures of Cayaponosides, New 29-Nor-1,2,3,4,5,10-hexadehydrocucurbitacin Glucosides
• Studies on the Constitutents of Aster scaber THUNB. V. Structures of Six New Echinocystic Acid Glycosides Isolated from the Herb
• STRUCTURES OF NEW NON-AROMATIZED NOR-CUCURBITACIN GLUCOSIDES IN THE ROOTS OF CAYAPONIA TAYUYA
• STRUCTURES OF CAYAPONOSIDES A, B, C AND D, GLUCOSIDES OF NEW NOR-CUCURBITACINS IN THE ROOTS OF CAYAPONIA TAYUYA
• Studies on the Constituents of Aster scaber THUNB. III. Structures of Scaberosides B_7,B_8 and B_9,Minor Oleanolic Acid Glycosides Isolated from the Root
• Parsonsianine, a Macrocyclic Pyrrolizidine Alkaloid from the Leaves of Parsonsia laevigata (Studies on Parsonsia, III)
• Studies on the Constituents of Aster tataricus L. f. III. : Structures of Aster Saponins E and F Isolated from the Root
• Antiproliferative Constituents from Umbelliferae Plants VII. Active Triterpenes and Rosmarinic Acid from Centella asiatica(Pharmacognosy)
• 72 メキシコ産植物のアレロパシー活性の検索 : メタノール抽出液を用いた一次スクリーニング(1-(3)雑草害、競争、他感作用)(1. 雑草)
• Studies on Xanthoxylum spp. II. Constituents of the Bark of Xanthoxylum piperitum DC.
• Four New Lignans, Xanthoxylol, Piperitol and Their γ, γ-Dimethylallyl Ethers, from Xanthoxylum piperitum Bark
• 薬学教育年限延長の有効活用を!(21世紀の人づくり)(21世紀:薬学の時代へ)
• Strophanthidin Glycosides from the Roots of Apocynum venetum var. : basikurumon : Studies on Apocynum. II
• Pregnanes and Pregnane Glycosides from the Roots of Apocynum venetum var. basikurumon : Apocynum. I(Organic,Chemical)
• Glycosides of 14,15-Seco-and 13,14 : 14,15-Disecopregnanes from the Roots of Tylophora tanakae
• 14-Deoxyparsonsianidine N-Oxide : A Pyrrolizidine Alkaloid Sequestered by the Giant Danaine Butterfly, Idea leuconoe
• Trypanocidal Constituents in Plants 4. Withanolides from the Aerial Parts of Physalis angulata(Pharmacognosy)
• Interactions of Phytoestrogens with Estrogen Receptors α and β(III). Estrogenic Activities of Soy Isoflavone Aglycones and Their Metabolites Isolated from Human Urine(Toxicology)
• Trypanocidal Constituents in Plants 3. Leaves of Garcinia intermedia and Heartwood of Calophyllum brasiliense(Pharmacognosy)
• Trypanocidal Constituents in Plants 2. Xanthones from the Stem Bark of Garcinia subelliptica (Pharmacognosy)
• The Survey of Trypanocidal Constituents in Some Mexican Plants
• 抗トリパノソーマ活性を有する植物成分の研究
• Ursolic Acid as a Trypanocidal Constituent in Rosemary
• Activity-Guided Fractionation of Green Tea Extract with Antiproliferative Activity against Human Stomach Cancer Cells
• Trypanocidal Constituents in Plants 1. Evaluation of Some Mexican Plants for Their Trypanocidal Activity and Active Constituents in Guaco, Roots of Aristolochia taliscana
• Antiproliferative Constituents in Plants 9. Aerial Parts of Lippia dulcis and Lippia canescens
• Antiproliferative Constituents in Plants 10. Flavones from the Leaves of Lantana montevidensis BRIQ. and Consideration of Structure-Activity Relationship
• HIV-1 Inhibitory Compounds from Calophyllum brasiliense Leaves(Pharmacognosy)
• Nematocidal Effects of Mexican-Medicinal Plant Extracts(Research note)
• Trypanocidal Activity and Chemistry of Several Guttiferae Species from Mexico
• Ursolic Acid as a Trypanocidal Constituent in Rosemary
• 抗菌活性を有するメキシコ産薬用植物のスクリーニング
• Antiproliferative Constituents in the Plants 7. Leaves of Clerodendron bungei and Leaves and Bark of C. trichotomum^
• Studies on the Constituents of Mallotus japonicus MUELL. ARG. I. Cardiac Glycosides from the Seeds
• Antiproliferative Constituents in the Plant 8. Seeds of Rhynchosia volubilis
• Antiproliferative Constituents from Umbelliferae Plants. IX. New Triterpenoid Glycosides from the Fruits of Bupleurum rotundifolium
• Antiproliferative Constituents from Umbelliferae Plants VI. New Ursane-Type Saikosaponin Analogs from the Fruits of Bupleunim rotundifolium
• Steroidal Constituents from the Roots and Stems of Asclepias fruiticosa
• Studies on the Constituents of Aster tataricus L.f. II. : Structures of Aster Saponins Isolated from the Root
• Studies on the Constituents of Luffa operculata COGN. II. : Isolation and Structure Elucidation of Saponins in the Herb
• Reaction of Epoxides. II. Synthesis of Oxazolidine by the Reaction of Epoxide with Schiff Base
• 腫瘍細胞増殖抑制作用を有するフェノール性植物成分と構造活性相関 (特集 植物資源の新機能の探索(1))
• Pregnane Glycosides from Marsdenia tomentosa
• Studies on the Constituents of Momordica cochinchinensis SPRENG. II. Isolation and Characterization of the Root Saponins, Momordins I, II and III
• STRUCTURES OF MOMORDICINES I, II AND III, THE BITTER PRINCIPLES IN THE LEAVES AND VINES OF MOMORDICA CHARANTIA L.
• Examination for Estrogenic Activities of Soyasaponin I and Related Compounds
• Soy Isoflavone Metabolites Isolated from Human Urine
• Antiproliferative Activity of Phenylpropanoid Ester Glycosides from Ligustrum purpurascens
• HPLC Profile Analysis of Hepatoprotective Oleanene-Glucuronides in Several Soybean Processed Foods
• Studies on the Constituents of Momordica charantia L. IV. Characterization of the New Cucurbitacin Glycosides of the Immature Fruits. (2) Structures of the Bitter Glycosides, Momordicosides K and L
• Studies on the Constituents of Momordica charantia L. III. Characterization of New Cucurbitacin Glycosides of the Immature Fruits. Structures of Momordicosides G, F_1,F_2 and I
• Studies on the Constituents of Momordica charantia L. II. Isolation and Characterization of Minor Seed Glycosides, Momordicosides C, D and E
• Screening of promising chemotherapeutic candidates against human adult T-cell leukemia/lymphoma from plants : active principles from Physalis pruinosa and structure-activity relationships with withanolides
• Studies on the Constituents of Luffa operculata COGN. I. : Isolation and Structures of Luperosides A-H, Dammarane-Type Triterpene Glycosides in the Herb
• Studies on the Constituents of Aster tataricus L. f. I. : Structures of Shionosides A and B : Monoterpene Glycosides Isolated from the Root

もっと見る 閉じる

スポンサーリンク