Enzymatic Production of (S)-1-Acetoxy-2-Alkanol with Bakers' Yeast Cell-Free Extract in a Membrane Reactor
スポンサーリンク
概要
- 論文の詳細を見る
The effective production and extraction of (S)-1-acetoxy-2-alkanol has been achieved using a bakers' yeast cell-free extract in a membrane reactor. 1-Acetoxy-2-alkanones were reduced to (S)-1-acetoxy-2-alkanols with high optical purities (>98% ee) without hydrolysis of the α-acetoxy group. This reactor system required neither the isolation of the enzyme for the reduction of the substrate nor the addition of the enzymes participating the cofactor (NADPH) regeneration. Futhermore, the system needs not immobilize these enzymes to a carrier. The productive efficiency did not decrease during repetitive batch reductions.
- 社団法人日本生物工学会の論文
- 1996-03-25
著者
-
中村 薫
京都大学化学研究所
-
中島 伸佳
Graduate School Of Health And Welfare Okayama Prefectural University
-
中島 伸佳
岡山県立大学短期大学部
-
中島 伸佳
岡山県立短大
-
NAKAJIMA Nobuyoshi
Department of Nutritional Science, Okayama Prefectural University
-
ISHIHARA Kohji
Department of Chemistry, Kyoto University of Education
-
NAKAMURA Kaoru
Institute for Chemical Research, Kyoto University
-
HIGASHI YUJI
Department of Applied Chemistry, Faculty of Engineering, Okayama University
-
UTAKA MASANORI
Department of Applied Chemistry, Faculty of Engineering, Okayama University
-
中村 薫
京大 化研
-
Ishihara K
Dep. Of Life Sci. Okayama Univ. Of Sci. 1-1 Ridai-cho Kita-ku Okayama 700-0005 Jpn
-
Nakajima Nobuyoshi
Graduate School Of Health And Welfare Okayama Prefectural University
-
Nakajima Nobuyoshi
Department Of Nutritional Science Faculty Of Health And Welfare Okayama Prefectural University
-
Nagahama Kazuhiro
Department Of Applied Microbial Technology The Kumanoto Institute Of Technology
-
Nakamura Kaoru
Institute For Chemical Research Kyoto University
-
Utaka M
Department Of Applied Chemistry Faculty Of Engineering Okayama University
-
Higashi Yuji
Department Of Applied Chemistry Faculty Of Engineering Okayama University
-
Utaka Masanori
Department Of Applied Chemistry Faculty Of Engineering Okayama University
-
Utaka Masanori
Department Of Synthetic Chemistry School Of Engineering Okayama University
-
Nakamura Kahoru
Department Of Nutrition Tokyo University Of Agriculture
-
Nakajima Nobuyoshi
Department of Food and Nutrition, Okayama Prefectural Junior College
関連論文
- 生育光条件の異なるブロッコリースプラウトが腸管上皮細胞からのIL-7・TGF-β分泌に及ぼす影響
- イソクエルシトリンによるアコヤガイ赤変病の軽減
- 植物性素材を原料とした「乳酸菌・酵母発酵エキス(PELY)」に関する研究
- エコシステムを利用した瀬戸内海沿岸の海洋環境汚染物質の除去・回収法の開発--環境ホルモン関連物質を中心として
- 瀬戸内海総合開発特別研究(第36回伊原木記念賞)エコシステムを利用した瀬戸内海沿岸の海洋汚染物質の除去・回収法の開発
- 海洋性微細藻類を用いる内分泌攪乱物質(環境ホルモン)の機能改変と海洋汚染物質の除去に関する研究
- 食品添加物としての、天然植物色素の酵素的安定化と、抗酸化性を中心としたそれらの付随的生理機能の解明
- P-12 植物培養細胞による活性フェノール化合物の配糖化(ポスター発表の部)
- 超臨界二酸化炭素中の酵素反応による有用物質の新規効率的合成
- 超臨界二酸化炭素中における環境調和型バイオ触媒反応 (特集 環境触媒の開発と技術)
- 不斉還元における生体触媒法と化学法の違い (特集 生体触媒反応とプロセス)
- 超臨界二酸化炭素を利用した生体触媒反応の開発--リパーゼ、アルコール脱水素酵素、脱炭酸酵素の反応 (超臨界最新技術特集第6号)
- 超臨界二酸化炭素中におけるバイオプロセス (特集 超臨界二酸化炭素中における有機合成反応)
- 解説 生体触媒による有用物質変換と環境浄化
- 生体触媒による有用物質変換のメリット・デメリット (特集/生体機能性化学の最前線)
- チチカビによる立体選択的酸化還元反応
- Further Characterization of Earthworm Serine Proteases : Cleavage Specificity Against Peptide Substrates and on Autolysis
- Multi-enzymatic Glucosylation Using Eucalyptus UDP-Glucosyltransferase Coupled UDPglucose-Fermentation by Bakers'Yeast
- Asymmetric Reduction of α-Keto Esters and α-Diketones with a Bakers' Yeast Keto Ester Reductase
- Lipase-catalyzed Synthesis of Arbutin Cinnamate in an Organic Solvent and Application of Transesterification to Stabilize Plant Pigments
- Preparation of Optically Active α-Hydroxy Esters : Stereoselective Reduction of α-Keto Esters Using Thermophilic Actinomycetes
- 生体触媒反応の人為的制御
- Amino Acid Sequence and Characterization of Aldo-keto Reductase from Bakers' Yeast
- Stereoselective Reduction of α- and β-Keto Esters with Aerobic Thermophiles, Bacillus Strains
- Protein Sequences of Two Keto Ester Reductases: Possible Identity as Hypothetical Proteins
- Enzymatic Production of (S)-1-Acetoxy-2-Alkanol with Bakers' Yeast Cell-Free Extract in a Membrane Reactor
- 光学分割剤としてのリパーゼと基質の相性診断
- 657 酵素共役反応系を用いるラセミ型アミノ酸から光学活性L-異性体への酵素的変換
- 2-I-23 NADH水素転移の立体化学 : NMRによるin situ解析法(第41回大会一般研究発表)
- 遺伝子組換え技術によるグルタミン酸ラセマ-ゼの酵素化学研究と,有用物質の酵素的生産
- ピリドキサルリン酸非依存性アミノ酸ラセマ-ゼ (1988年の化学-3-)
- A-8 乳酸菌のグルタミン酸ラセマーゼの反応機構(日本農芸化学会関西支部大会報告)
- 11.Bacillus stearothermophilusの新酵素,NAD要求性メゾジアミノピメリン酸脱水素酵素(第291回会議研究発表要旨,ビタミンB研究委員会)
- Multi-enzymatic Glucosylation Using Eucalyptus UDP-Glucosyltransferase Coupled UDPglucose-Fermentation by Bakers'Yeast
- Asymmetric Reduction of α-Keto Esters and α-Diketones with a Bakers' Yeast Keto Ester Reductase
- Amino Acid Sequence and Characterization of Aldo-keto Reductase from Bakers' Yeast
- Enzymatic Production of (S)-1-Acetoxy-2-Alkanol with Bakers' Yeast Cell-Free Extract in a Membrane Reactor
- A Novel Zinc-containing α-Keto Ester Reductase from Actinomycete : An Approach Based on Protein Chemistry and Bioinformatics
- P-337 Synthesis and Activity of Acyl-substituted Catechin, Epicatechin and Procyanidin dimers
- Degradation of Pectic Substances by Two Pectate Lyases from a Human Intestinal Bacterium, Clostridium butyricum-beijerinckii Group
- 成長に伴う鶏肝ヘキソナ-ゼおよび解糖系の変動
- Purification and Characterization of α-Keto Ester Reductases from Bakers' Yeast
- Differences in Protein Structure and Similarities in Catalytic Function of Two L-Stereoselective Carbonyl Reductases from Bakers' Yeast
- Enzymatic preparation of arbutin derivatives : Lipase-catalyzed direct acylation without the need of vinyl ester as an acyl donor(MICROBIAL PHYSIOLOGY AND BIOTECHNOLOGY)
- Synthesis of Unnatural Mono- and Oligosaccharides of Farnesol, Geraniol, and (S)-Perillyl Alcohol by Biocatalytic Glycosylations
- Enhancement of Water-Solubility and Bioactivity of Paclitaxel Using Modified Cyclodextrins(METHODS)
- 有機溶媒に耐性で常温においては自己消化による失活を伴わない「ミミズプロテアーゼ」の物質合成・変換への応用 (特集 物質合成の設計図にブレークスルーを--酵素触媒の活躍と未来)
- Analysis of Isoflavone Content in Tempeh, a Fermented Soybean, and Preparation of a New Isoflavone-Enriched Tempeh(BREWING AND FOOD TECHNOLOGY)
- An Isozyme of Earthworm Serine Proteases Acts on Hydrolysis of Triacylglycerol
- Biotransformation of (+)-catechin by plant cultured cells of Eucalyptus perriniana
- Purification and Characterization of α-Keto Amide Reductase from Saccharomyces cerevisiae
- Stereoselective biotransformation of limonene and limonene oxide by cyanobacterium, Synechococcus sp. PCC 7942
- Damage to Cultivated Japanese Pearl Oysters by Oxidative Stress That Was Related to "Mass Mortality"(Biochemistry & Molecular Biology)
- One- step Glucosylation of Capsaicinoids by Cultured Cells of Phytolacca americana
- Comparison of Acylated Plant Pigments : Light-resistance and Radical-scavenging Ability(Biochemistry & Molecular Biology)
- Further Stabilization of Earthworm Serine Protease by Chemical Modification and Immobilization(Biochemistry & Molecular Biology)
- Enzyme-catalyzed Acylation of Plant Polyphenols for Interpretation of Their Functions
- Stereoselective Reduction of Ketone and Enone using Plant Cell Cultures
- Purification and Characterization of Two α-Keto Ester Reductases from Streptomyces thermocyaneoviolaceus IFO 14271(Microbiology & Fermentation Technology)
- Functional Glucosylation of Kojic Acid and Daidzein with the Eucalyptus Membrane-Associated UDP-Glucosyltransferase Reaction System
- Stereocontrolled Reduction of α-and β-Keto Esters with Micro Green Algae, Chlorella Strains
- Regioselective Acylation of Flavonoid Glucoside with Aromatic Acid by an Enzymatic Reaction System from Cultured Cells of Ipomoea batatas
- カツオ(Katsuwonus pelamis)塩辛由来の新規な線溶プロテア-ゼ--精製と性質
- ミミズ(Lumbricus rubellus)細胞中に発見されたきわめて安定な線溶酵素-3-蛋白化学的性質と分子構造
- ミミズ(Lumbricus rubellus)細胞中に発見されたきわめて安定な線溶酵素-2-単離・精製と酵素科学的性質
- ミミズ(Lumbricus rubellus)細胞中に発見されたきわめて安定な線溶酵素-1-存在と性質,安定性
- 生体触媒の応用--酵素バイオリアクタ-を用いる各種の光学活性アミノ酸の新規な生物的合成・変換法の開発
- DNAアレイを用いた有機合成用触媒のハイスループットスクリーニング(バイオミディア)
- 光電子移動触媒存在下の補酸素NAD(P)Hによる脱スルホニル化反応の反応機構
- 微生物を用いた光学異性体の作り分け
- チオフィリックな反応
- Detoxifying Effect of Desalinated Deep Seawater on Organotin-poisoned Euglena gracilis(Food & Nutrition Science)
- Detoxification Effect of Iron-encaging Zeolite-processed Water in Tributyltin-intoxicated Euglena gracilis Z
- Effect of Several Solutions Including Mineral-encaging Zeolites on the Restoration of Cell Motility of Tributyltin-intoxicated Euglena gracilis Z
- Synthesis and Activity of Pyrimidinylpropenamide Antibiotics : The Alkyl Analogues of Sparsomycin(Organic Chemistry)
- Indocarbazostatin and Indocarbazostatin B, Novel Inhibitors of NGF-induced Neuronal Differentiation in PC12 Cells : II. Isolation, Physicochemical Properties and Structural Elucidation
- First Principles Calculations of Vacancy Formation Energies in *13 Pyramidal Twin Grain Boundary of α-Al_2O_3
- Stereochemical Control in Microbial Reduction. 30. Reduction of Alkyl 2-Oxo-4-phenylbutyrate as Precursors of Angiotensin Converting Enzyme (ACE) Inhibitors
- The NADPH : Quinone Oxidoreductase P1-ζ-crystallin in Arabidopsis Catalyzes the α, β-Hydrogenation of 2-Alkenals : Detoxication of the Lipid Peroxide-Derived Reactive Aldehdes
- Purification and Characterization of Konjac Glucomannan Degrading Enzyme from Anaerobic Human Intestinal Bacterium, Clostridium butyricum-Clostridium beijerinckii Group
- Chemical Modification of Earthworm Fibrinolytic Enzyme with Human Serum Albumin Fragment and Characterization of the Protease as a Therapeutic Enzyme
- Stable Earthworm Serine Proteases : Application of the Protease Function and Usefulness of the Earthworm Autolysate
- Stereoselective Reduction of Carbonyl Compounds with Actinomycete: Purification and Characterization of Three α-Keto Ester Reductases from Streptomyces avermitilis
- Effects of Additives in the Reduction Using Bakers' Yeast Cell-Free Extract
- Stereoselective Preparation of (R)-4-Nitro-2-butanol and (R)-5-Nitro-2-pentanol Mediated by a Lipase(Organic Chemistry)
- Rate Enhancement of Lipase-catalyzed Reaction in Supercritical Carbon Dioxide
- Purification and Characterization of Aldehyde Reductase from Leuconostoc dextranicum
- Synthetic Studies of Proanthocyanidins. Highly Stereoselective Synthesis of the Catechin Dimer, Procyanidin-B3(Organic Chemistry)
- A Sensitive Radial Diffusion Method for the Determination of Several Proteases
- 機能性食品としての海洋生物--無脊椎動物および藻類中に見出された血栓溶解関連物質
- Biotransformation of Cinnamic Acid, p-Coumaric Acid, Caffeic Acid, and Ferulic Acid by Plant Cell Cultures of Eucalyptus perriniana
- Stereoselective Reduction of Carbonyl Compounds with Actinomycete : Purification and Characterization of Three α-Keto Ester Reductases from Streptomyces avermitilis
- 血栓溶解酵素ナットウキナ-ゼの活性測定法
- Enzymatic Production of β-Thujaplicin 2-O-β-D-Glucoside in a Membrane Reactor Using an Insoluble UDP-Glucosyltransferase Fraction from Cultured Cells of Eucalyptus perriniana
- Lipase-Catalyzed Direct and Regioselective Acylation of Flavonoid Glucoside for Mechanistic Investigation of Stable Plant Pigments
- Stereoselective Reduction of Carbonyl Compounds Using the Cell-Free Extract of the Earthworm, Lumbricus rubellus, as a Novel Source of Biocatalyst
- 有機スズ曝露による細胞障害の機能水による回復
- 海洋生物と血栓溶解関連物質
- 微生物を用いた光学異性体の作り分け
- Glycosylation of trans-Resveratrol by Plant-Cultured Cells