Effects of Dietary Soybean Peptides on Hepatic Production of Ketone Bodies and Secretion of Triglyceride by Perfused Rat Liver
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概要
- 論文の詳細を見る
Soybean protein isolate (SPI) was digested with protease to produce a peptides containing the low-molecular fraction (LD3) or a mixture of high- and low-molecular fractions (HD1). Rats were fed a diets containing SPI, LD3, or HD1 at a protein level equivalent to the 20% casein diet for 4 weeks. The serum triglyceride concentration was lower in rats fed SPI, LD3, and HD1 diets than in rats fed the casein diet, and the differences were significant for the cholesterol-enriched diet. The value for the LD3 group was the lowest among all groups for both the cholesterol-free and -enriched diets. The level of triglyceride in the post-perfused liver was significantly lower in the LD3 and HD1 groups and the SPI group than in the casein group irrespective of the presence of cholesterol in the diet. In the cholesterol-free diet, LD3 feeding as compared to casein feeding caused a reduction in triglyceride secretion from the liver to perfusate and an increment of hepatic ketone body production. The addition of cholesterol to the diets somewhat attenuated these effects of LD3. These results suggest that the low-molecular fraction in soybean peptides causes triglyceride-lowering activity through a reduction in triglyceride secretion from the liver to the blood circulation and the stimulation of fatty acid oxidation in the liver. There is a possibility that soybean peptides modulate triglyceride metabolism by changes in the hepatic contribution.
- 社団法人 日本農芸化学会の論文
- 2007-10-23
著者
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Sugano Michihiro
Faculty of Agriculture, Kyushu University
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FUKUDA Nobuhiro
Department of Biochemistry and Applied Biosciences, Faculty of Agriculture, Miyazaki University
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Sugano M
Faculty Of Environmental And Symbiotic Sciences Prefectural University Of Kumamoto
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Sugano M
Faculty Of Environmental And Symbiotic Science Prefectural University Of Kumamoto
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Sugano Michihiro
Kumamoto Prefecture University
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Ki Masami
Laboratory Of Food And Biomolecular Science Graduate School Of Agricultural Science Tohoku Universit
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Sakono M
Laboratory Of Nutrition Chemistry Faculty Of Agriculture Graduate School Of Kyushu University
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Sato M
Laboratory Of Nutrition Chemistry Faculty Of Bioresources And Bioenvironmental Sciences Graduate Sch
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SAKONO Masanobu
Department of Food Science and Technology, Faculty of Agriculture, Kyushu University
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SUGANO Michihiro
Prefectural University of Kumamoto
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Sugano M
Kumamoto Prefectural Univ. Kumamoto Jpn
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Sugano Michihiro
Faculty Of Environmental And Symbiotic Science Prefectural University Of Kumamoto
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Sugano Michihiro
Fac. Of Environmental And Symbiotic Sciences Prefectural Univ. Of Kumamoto
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Sugano Michihiro
Laboratory Of Nutrition Chemistry Kyushu University School Of Agriculture
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TANAKA Kazunari
Graduate School of Human Health Science, Siebold University of Nagasaki
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Sakono Masanobu
Department Of Biochemistry And Applied Biosciences Faculty Of Agriculture University Of Miyazaki
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Sakono Masanobu
Department Of Biological Resource Sciences Faculty Of Agriculture Miyazaki University
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Fukuda Nobuhiro
Dep. Of Biochemistry And Applied Biosciences Fac. Of Agriculture Univ. Of Miyazaki
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Fukuda Nobuhiro
Department Of Biochemistry And Applied Biosciences Faculty Of Agriculture Miyazaki University
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Sugano M
Laboratory Of Food Chemistry Division Of Bioresource And Bioenvironmental Sciences Graduate School K
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TAMARU Shizuka
Department of Biochemistry and Applied Biosciences, Faculty of Agriculture, Miyazaki University
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Kudo Mariko
Laboratory Of Nutrition Chemistry Faculty Of Agriculture Graduate School Of Kyushu University
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Fukuda N
Univ. Miyazaki Miyazaki Jpn
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Sakono Masanobu
Dep. Of Biochemistry And Applied Biosciences Fac. Of Agriculture Univ. Of Miyazaki
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Noda Takahiro
Fuji Oil Co. Ltd. Research & Development Institute
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Furuta Hitoshi
Fuji Oil Co. Ltd. Research & Development Institute
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KURAYAMA Takayuki
Department of Biochemistry and Applied Biosciences, Faculty of Agriculture, University of Miyazaki
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NAKAMORI Toshihiro
Fuji Oil Co., Ltd., Research & Development Institute
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Tanaka Kazunari
Graduate School Of Human Health Science University Of Nagasaki
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Tamaru Shizuka
Department Of Biochemistry And Applied Biosciences Faculty Of Agriculture University Of Miyazaki
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Kurayama Takayuki
Department Of Biochemistry And Applied Biosciences Faculty Of Agriculture University Of Miyazaki
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Nakamori Toshihiro
Fuji Oil Co. Ltd Hannan Research And Development Center
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Tanaka Kazunari
Graduate School Of Human Health Sci. Siebold Univ. Of Nagasaki
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Tanaka Kazunari
Graduate School Of Human Health Science Siebold University Of Nagasaki
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Furuta Hitoshi
Fuji Oil Co. Ltd Hannan Research And Development Center
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Kobayashi Makoto
Laboratory Of Nutrition Chemistry Department Of Bioscience And Biotechnology Faculty Of Agriculture
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Kudo Mariko
Laboratory of Food and Biomolecular Science, Graduate School of Agricultural Science, Tohoku University
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