Anti-Obesity and Hypotriglyceridemic Properties of Coffee Bean Extract in SD Rats
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概要
- 論文の詳細を見る
Coffee bean extract (CBE) was prepared from raw green coffee beans and contained 10.0% caffeine and 27.0% chlorogenic acid. Male Sprague-Dawley rats were fed a diet containing 1% CBE for 4 weeks. Although there was no difference in food intake between rats fed the control diet without CBE and those fed the CBE-containing diet, body weight gain and white adipose tissue weight were significantly decreased in CBE-fed rats than in control rats. The CBE-fed group exerted a significant and extreme reduction in serum and liver triglyceride concentrations compared to the control group. Also, in the CBE-fed group, activities of fatty acid synthetic enzymes in the hepatic cytosol were significantly decreased, while that of fatty acid oxidative enzymes in the hepatic mitochondria was significantly increased. Our results suggest that CBE has potent anti-obesity and hypotriglyceridemic properties, and there is a possibility that these effects are exerted at least in part by the suppression of lipogenesis and the acceleration of lipolysis.
- 社団法人 日本食品科学工学会,Japanese Society for Food Science and Technologyの論文
- 2009-03-01
著者
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SHIMODA Hiroshi
Research and Development Division, Morishita Jintan Co., Ltd.
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Nishizono Shoko
Graduate School Of Human Health Science Siebold University Of Nagasaki
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TANAKA Kazunari
Graduate School of Human Health Science, Siebold University of Nagasaki
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Tamaru Shizuka
Graduate School of Human Health Science, University of Nagasaki
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KONDO Mihoko
Graduate School of Human Health Science, University of Nagasaki
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TANAKA Junji
Research & Development Division, Oryza Oil & Fat Chemical Co., Ltd.
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OKADA Tadashi
Research & Development Division, Oryza Oil & Fat Chemical Co., Ltd.
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Kawasaki T
Industrial Technol. Center Of Nagasaki
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Shimoda Hiroshi
Research & Development Division Oryza Oil & Fat Chemical Co. Ltd.
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Tanaka Junji
Research & Development Division Oryza Oil & Fat Chemical Co. Ltd.
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Okada Tadashi
Research & Development Division Oryza Oil & Fat Chemical Co. Ltd.
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Kawasaki T
Institute Of Health Science Kyushu University : (present) H.s Division Of Endocrine And Diabetic Med
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Kondo Mihoko
Graduate School Of Human Health Science University Of Nagasaki
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Nishida Satoko
Laboratory Of Nutrition Chemistry Faculty Of Bioresources And Bioenvironmental Sciences Graduate Sch
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Kawasaki Terukazu
Institute Of Health Science Kyuhu University
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Nishida S
Graduate School Of Human Health Science University Of Nagasaki
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Tanaka Kazunari
Graduate School Of Human Health Science University Of Nagasaki
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Tamaru Shizuka
Graduate School Of Human Health Science University Of Nagasaki
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Tanaka Kazunari
Graduate School Of Human Health Sci. Siebold Univ. Of Nagasaki
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