Reactions of 1,4-bis(trimethylsilyl)-1,4-dihydropyridines with carbonyl compounds : A new method for regioselective synthesis of 3-alkylpyridines.
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概要
- 論文の詳細を見る
A new method for the alkyl group introduction at the 3-position of pyridienes is described: Reductive disilylation of pyridine, its 2-methyl, 3-methyl, and 4-methyl derivatives affords the corresponding 1,4-disilyl-1,4-dihydropyridines. In the presence of a catalytic amount of tetrabutylammonium fluoride, these dihydropyridines smoothly react with a variety of aldehydes and ketones to give 3-alkylpyridines.
- 公益社団法人 日本化学会の論文
著者
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TANAKA Junji
Research & Development Division, Oryza Oil & Fat Chemical Co., Ltd.
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Tsuge Otohiko
Research Institute of Industrial Science, and Department of Molecular Science and Technology, Interdisciplinary Graduate School of Engineering Sciences Kyushu University
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Tanaka Junji
Research Institute of Industrial Science, and Department of Molecular Science and Technology, Interdisciplinary Graduate School of Engineering Sciences, Kyushu University
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Kanemasa Shuji
Research Institute of Industrial Science, and Department of Molecular Science and Technology, Interdisciplinary Graduate School of Engineering Science, Kyushu University
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Naritomi Toshio
Research Institute of Industrial Science, and Department of Molecular Science and Technology, Interdisciplinary Graduate School of Engineering Sciences, Kyushu University
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