Stereoselective cycloadditions of pyridinium or isoquinolinium methylides with olefinic dipolarophiles and subsequent cycloadditions of the cycloadducts with nitrile oxides.
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概要
- 論文の詳細を見る
Pyridinium or isoquinolinium methylides undergo highly stereo- and regioselective cycloadditions with olefinic dipolarophiles to form unstable tetrahydroindolizine derivatives. One of the two double bonds existing in the dihydro heteroaromatic ring of the cycloadducts reacts with nitrile oxides, in the same flask, in stereo-, regio-, and periselective fashions to lead to stable isoxazole-fused tetrahydroindolizines in good yields.
- 公益社団法人 日本化学会の論文
著者
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Tsuge Otohiko
Research Institute of Industrial Science, and Department of Molecular Science and Technology, Interdisciplinary Graduate School of Engineering Sciences Kyushu University
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Takenaka Shigeori
Research Institute of Industrial Science, and Department of Molecular Science and Technology, Interdisciplinary Graduate School of Engineering Sciences, Kyushu University
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Kanemasa Shuji
Research Institute of Industrial Science, and Department of Molecular Science and Technology, Interdisciplinary Graduate School of Engineering Science, Kyushu University
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