P-38 ANALYSIS OF CH/π INTERACTION BETWEEN TUMOR PROMOTERS AND PROTEIN KINASE C C1 DOMAINS

スポンサーリンク

概要

• 論文の詳細を見る
• 天然有機化合物討論会の論文
• 2006-07-23

著者

• Ohigashi H

  Department Of Surgery Osaka Medical Center For Cancer And Cardiovascular Diseases

• Ohigashi Hiroaki

  Department Of Surgery The Center For Adult Diseases

• 入江 一浩

  京都大学農学部

• 入江 一浩

  京都大学 食品工学

• 入江 一浩

  京都大学 農

• 入江 一浩

  京都大学大学院農学研究科食品生物科学

• Nakamura Yoshimasa

  Division Of Applied Life Sciences Graduate School Of Agriculture Kyoto University

• Nakamura Y

  Division Of Applied Life Sciences Graduate School Of Agriculture Kyoto University

• Ohigashi H

  Graduate School Of Agriculture Kyoto University

• Ohigashi Hajime

  Graduate School Of Agriculture Kyoto University

• Ohigashi H

  Division Of Applied Life Sciences Graduate School Of Agriculture Kyoto University

• Nakagawa Y

  Graduate School Of Agriculture Kyoto University

• Nakagawa Yu

  Graduate School Of Agriculture Kyoto University

• Yanagita Ryo

  Graduate School Of Agriculture Kyoto University

• Irie Kazuhiro

  京都大学 農学研究科

• Nakagawa Yasue

  Department Of Food Faculty Of Home Economics Jissen Women's University

• IRIE Kazuhiro

  Graduate School of Agriculture, Kyoto University

• Irie Kazuhiro

  Graduate School Of Agriculture Kyoto University

• Yamanaka Nobuhiro

  Graduate School of Agriculture, Kyoto University

• 入江 一浩

  Division Of Food Science And Biotechnology Graduate School Of Agriculture Kyoto University

• Yamanaka Nobuhiro

  Graduate School Of Agriculture Kyoto University

• Nakagawa Yu

  Division Of Food Science And Biotechnology Graduate School Of Agriculture Kyoto University

関連論文

• EphA4 receptor, overexpressed in pancreatic ductal adenocarcinoma, promotes cancer cell growth
• Novel tumor marker REG4 detected in serum of patients with resectable pancreatic cancer and feasibility for antibody therapy targeting REG4
• Usefulness of the CLIP scoring system for prediction of postoperative prognosis of patients with large hepatocellular carcinoma
• Identification of C2orf18, termed ANT2BP (ANT2-binding protein), as one of the key molecules involved in pancreatic carcinogenesis
• Over-expression of cysteine proteinase inhibitor cystatin 6 promotes pancreatic cancer growth
• Periodic Ultrasonography Checkup for the Early Detection of Pancreatic Cancer : Preliminary Report
• Unusual Atrophic Change After Repeated Arterial Therapy for Hepatocellular Carcinoma : Report of a Case
• Acinar Cell Carcinoma of the Pancreas Successfully Treated by En Bloc Resection and Intraperitoneal Chemotherapy for Peritoneal Relapse : A Case Report of a 15-Year Survivor
• 1995年度日本農芸化学会大会【encircled 1】
• An Avocado Constituent, Persenone A, Suppresses Expression of Inducible Forms of Nitric Oxide Synthase and Cyclooxygenase in Macrophages, and Hydrogen Peroxide Generation in Mouse Skin
• Inhibition by (-)-Persenone A-related Compounds of Nitric Oxide and Superoxide Generation from Inflammatory Leukocytes
• Inhibitory Effects of Curcumin and Tetrahydrocurcuminoids on the Tumor Promoter-induced Reactive Oxygen Species Generation in Leukocytes in vitro and in vivo
• Auraptene, a Citrus Coumarin, Inhibits 12-O-Tetradecanoylphorbol-13-acetate-induced Tumor Promotion in ICR Mouse Skin, Possibly through Suppression of Superoxide Generation in Leukocytes
• Identitication of Pheophorbide a and Its Related Compounds as Possible Anti-tumor Promoters in the Leaves of Neptunia oleracea
• 5 発がんプロモーター・インドラクタムの活性コンフォメーション(口頭発表の部)
• 発癌プロモーター・インドラクタムの活性コンフォメーション : 有機化学,天然物化学
• アミロイドβ(Aβ42)の毒性コンホメーションの提唱
• P-55 βアミロイドの新しい凝集モデルに基づく神経細胞毒性発現機構(ポスター発表の部)
• 11 固体NMRならびにESRによるβアミロイド(Aβ42)の毒性コンホメーションの解析(口頭発表の部)
• 1996年度日本農芸化学会大会 (1)
• 発癌プロモーター・テレオシジンの作用機構に関する有機化学的研究
• 4(A-4) CH/π相互作用に着目したプロテインキナーゼCアイソザイム選択的な薬剤の分子設計(口頭発表の部)
• ペプチド合成によるホルボールエステル受容体の機能解析
• 連載講座 「もの」が語るバイオサイエンス(6)ペプチド合成によるホルボールエステル受容体の機能解析
• 113(P-62) 発がんプロモーター・インドラクタムVのコンホメーション固定によるプロテインキナーゼCアイソザイム選択的リガンドの分子設計(ポスター発表の部)
• プロテインキナーゼCのシステインリッチドメインの化学合成, 機能解析とドラッグデザイン
• 新規光反応性フォルポールエステルを用いたプロテインキナーゼC調節領域の光アフィニティーラベリング : 有機化学・天然物化学
• Effects of Gum Arabic and Pectin on the Emulsification, the Lipase Reaction, and the Plasma Cholesterol Level in Rats(Food & Nutrition)
• ポリフェノールによるアルツハイマー病予防の可能性
• βアミロイドの毒性コンホメーション
• 26 天然発がんプロモーターの骨格を利用した抗がん剤bryostatin等価体の開発(口頭発表の部)
• 'Malignant' Conformation of Alzheimer's β Peptides (Aβ42) through Radical Formation
• P-64 ELUICIDATION OF THE 'MALIGNATNT' CONFORMATION OF β-AMYLOID WITH ITALIAN MUTATION (E22K-Aβ42) USING SOLID-STATE NMR
• P-9 FORMATION AND STABILIZATION MECHANISM OF THE β-AMYLOID RADICAL
• Structure of β-Amyloid Fibrils and Its Relevance to Their Neurotoxicity : Implications for the Pathogenesis of Alzheimer's Disease
• Synthesis and Tumor-promoting Activities of 12-Epi-phorbol-12,13-dibutyrate
• Synthesis and Biological Activities of (-)-6-n-Octyl-indolactam-V, a New Potent Analogue of the Tumor Promoter (-)-Indolactam-V
• Synthesis and Biological Activities of Indolactone-V, the Lactone Analogue of the Tumor Promoter (-)-Indolactam-V
• Photocytotoxicity of Water-soluble Fullerene Derivatives
• Antimutagenic and Anticarcinogenic Properties of Kyo-yasai, Heirloom Vegetables in Kyoto
• 微生物転換を用いた6位置換インドラクタムの合成研究 : 有機化学,天然物化学
• 6 プロテインキナーゼCのホルボールエステル結合部位を含むサロゲートペプチドの合成と化学的特性(口頭発表の部)
• Kurosu, a Traditional Vinegar Produced from Unpolished Rice, Suppresses Lipid Peroxidation in Vitro and in Mouse Skin
• Possible Anti-tumor Promoting Properties of Edible Plants from Thailand, and Identification of an Active Constituent, Cardamonin, of Boesenbergia pandurata
• Antitumoral and Antimicrobial Activities of Bitter Sesquiterpene Lactones of Vernonia amygdalina, a Possible Medicinal Plant Used by Wild Chimpanzees
• Antischistosomal Activities of Sesquiterpene Lactones and Steroid Glucosides from Vernonia amygdalina, Possibly Used by Wild Chimpanzees against Parasite-related Diseases
• Hypocholesterolemic Effect of Chitosan in Adult Males
• Metabolism of ^C-Isomaltooligosaccharides in Healthy Men
• Theasaponin E_1 Destroys the Salt Tolerance of Yeasts
• Physiological Characteristics of a Film-forming Strain of Zygosaccharomyces rouxii, and Its Cellular Fatty Acid Synthesis
• Possible Anti-tumor Promoting Properties of Marine Algae and In Vivo Activity of Wakame Seaweed Extract
• フォルボールエステルのジアジリン誘導体の合成と特性 : 有機化学・天然物化学
• マウス皮膚PKC_ηの調節領域モデルペプチドの合成とその生化学的特性 : 有機化学・天然物化学
• P-38 ANALYSIS OF CH/π INTERACTION BETWEEN TUMOR PROMOTERS AND PROTEIN KINASE C C1 DOMAINS
• Binding Selectivity of Conformationally Restricted Analogues of (-)-Indolactam-V to the C1 Domains of Protein Kinase C Isozymes(Organic Chemistry)
• Selective Binding of Tumor Promoters to the Novel PKC C1B Domains
• Isolation of (-)-14-O-Malonylindolactam-V as a Possible Precursor of (-)-Indolactam-V and (-)-14-O-Acetylindolactam-V from Streptomyces blastmyceticum
• Inhibition of Pancreatic Carcinogenesis by Shark Cartilage Proteoglycan in Hamsters
• Evidence for the Existence of a Soybean Resistant Protein That Captures Bile Acid and Stimulates Its Fecal Excretion
• Simple and rapid chromatographic purification of type V collagen from a pepsin digest of porcine intestinal connective tissue, an unmanageable starting material for conventional column chromatography
• DNA Repair Effect of Traditional Sweet Pepper Fushimi-togarashi : Seen in Suppression of UV-induced Cyclobutane Pyrimidine Dimer in Human Fibroblast
• Tumor-Promoting Phorbol Esters Bind Directly to the Regulatory Domain of Diacylglycerol Kinase Gamma
• Synthesis and Characterization of Model Peptides Incorporating the Phorbol Ester-binding Domain of Protein Kinase C
• Tyrosine-83 of Human Renin Contributes to Biphasic pH Dependence of the Renin-Angiotensinogen Reaction
• Non-proteolytic Activation of Human Prorenin by Anti-prorenin Prosegment (pf#1 : 1P-15P) Antiserum
• 発がんプロモーターのnPKC C1B ドメインへの選択的結合
• Feedback-regulated expression of brassinosteroid biosynthetic gene DWF4 in Arabidopsis
• Effects of Brassinolide and a specific inhibitor of brassinosteroid biosynthesis, Brassinazole on growth of Arabidopsis seedlings
• MOLECULAR CLONING OF ARABIDOPSIS GENES INVOLVED IN ROSETTE LEAF FORMATION BY DIFFERENTIAL DISPLAY TECHNIQUE
• New Aggregation Model of Amyloid β by the Systematic Proline Replacement
• Synthesis and Phorbol Ester Binding of the Zinc-finger Like Sequences of All Protein Kinase C Isozymes
• Apoptosis-inducing Activity of High Molecular Weight Fractions of Tea Extracts
• Apoptosis-inducing Activity of Polyphenol Compounds Derived from Tea Catechins in Human Histiolytic Lymphoma U937 Cells
• Identification of Toxic Conformation in Aβ42 Aggregates Using Solid-state NMR
• Angiotensin III as Well as Angiotensin II Regulates Water Flow through Aquaporins in a Clam Worm
• Effects of Substitution of Val for Leu^ of Oive Angiotensinogen on Renin Activity
• Silymarin Attenuated the Amyloid β Plaque Burden and Improved Behavioral Abnormalities in an Alzheimer's Disease Mouse Model
• The turn formation at positions 22 and 23 in the 42-mer amyloid β peptide : The emerging role in the pathogenesis of Alzheimer's disease
• Verification of the Intermolecular Parallel β-Sheet in E22K-Aβ42 Aggregates by Solid-State NMR Using Rotational Resonance : Implications for the Supramolecular Arrangement of the Toxic Conformer of Aβ42
• CH/π相互作用を利用した薬剤開発(最前線,ポストゲノム時代の有機化学)
• Exogenous Proline and Glycinebetaine Suppress Apoplastic Flow to Reduce Na^+ Uptake in Rice Seedlings
• The Involvement of Intracellular Glutathione in Methyl Jasmonate Signaling in Arabidopsis Guard Cells
• The Coexistence of Ser84 in Renin and His13 in Angiotensinogen Brings a pH Profile of Two Separate Peaks to the Reaction of Human Renin and Sheep Angiotensinogen
• Ser84 of Human Renin Contributes to the Biphasic pH Dependence of the Renin-Angiotensinogen Reaction
• Efficient Production of Recombinant Human (Pro)renin Utilizing a Decahistidine Tag Attached at the C-Terminus
• Surgical Resection for Hepatocellular Carcinoma with Metastasis to the Gallbladder : Report of a Case
• プロテインキナーゼ C 機能ドメインの化学合成
• プロテインキナーゼCの2つのzinc fingerモチーフの機能と役割
• Teleocidin類の構造活性相関と蛍光標識化
• プロテインキナーゼCのホルボールエステル結合部位の光アフィニティーラベリングによる構造解析
• プロテインキナーゼCのホルボールエステル結合部位の合成と化学的特性
• Synthesis and Biological Evaluation of the 12,12-Dimethyl Derivative of Aplog-1, an Anti-Proliferative Analog of Tumor-Promoting Aplysiatoxin
• 33. 気孔形成を調節するペプチドホルモンの機能解析(口頭発表,植物化学調節学会第46回大会)
• The Roles of CATALASE2 in Abscisic Acid Signaling in Arabidopsis Guard Cells
• プロテインキナーゼCのホルボールエステル結合部位の合成と化学的特性
• Stimulation of the Amyloidogenic Pathway by Cytoplasmic Superoxide Radicals in an Alzheimer's Disease Mouse Model
• Identification and Biological Activities of Bryostatins from Japanese Bryozoan
• Effects of Exogenous Proline and Glycinebetaine on the Salt Tolerance of Rice Cultivars
• Catalases CAT1 and CAT3 Are not Key Enzymes in Alleviating Gamma Irradiation-Induced DNA Damage, H2O2 Accumulation, or Lipid Peroxidation in Arabidopsis thaliana
• Effects of Depletion of Glutathione on Abscisic Acid- and Methyl Jasmonate-Induced Stomatal Closure in Arabidopsis thaliana

もっと見る 閉じる

スポンサーリンク